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ANTIPYRINE
ICSC: 0376
Peer-Review Status: 12.04.2013 Validated
1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
2,3-Dimethyl-1-phenyl-3-pyrazolin-3-one
Phenazone 
CAS #: 60-80-0 RTECS #: CD2450000
EINECS #: 200-486-6
    Formula: C11H12N2O
Molecular mass: 188.2

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. 
Skin No acute symptoms expected.  Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety spectacles.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion No acute symptoms expected.  Do not eat, drink, or smoke during work.  Rinse mouth. Seek medical attention if you feel unwell. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
 
GHS Classification
Signal: Warning
Harmful if swallowed 
excl mark;warn

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong oxidants. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS OR WHITE POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes of nitrogen oxides. Reacts with strong oxidants. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of dust and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
May cause mechanical irritation to the eyes and respiratory tract. 

Effects of long-term or repeated exposure
The substance may have effects on the blood. This may result in anaemia. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 319°C
Melting point: 113°C
Relative density (water = 1): 1.19
Solubility in water: very good
Octanol/water partition coefficient as log Pow: 0,23  
 

NOTES
Health effects of exposure to the substance have not been investigated adequately. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations