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CAFFEINEICSC: 0405
1,3,7-Trimethylxanthine
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Methyltheobromine
Methyltheophylline
March 1998
CAS #: 58-08-2
UN #: 1544
EC Number: 200-362-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, dry powder.   

 PREVENT DISPERSION OF DUST!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation See Ingestion.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Headache. Dizziness. Abdominal cramps. Nausea. Vomiting. Convulsions. Tremor.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1 

STORAGE
Separated from food and feedstuffs. Well closed. 
PACKAGING
Do not transport with food and feedstuffs. 
CAFFEINE ICSC: 0405
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
ODOURLESS WHITE CRYSTALS OR CRYSTALLINE POWDER. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. 

Formula: C8H10N4O2
Molecular mass: 194.19
Melting point: 235°C
Boiling point: 178°C (sublimes)
Density: 1.23 g/cm³
Solubility in water, g/100ml: 2.17
Octanol/water partition coefficient as log Pow: -0.07  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the central nervous system and cardiovascular system. This may result in insomnia, excitement, tachycardia and polyuria. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of long-term or repeated exposure
 


OCCUPATIONAL EXPOSURE LIMITS
 

ENVIRONMENT
Environmental effects from the substance have not been investigated adequately. 

NOTES
 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xn; R: 22; S: (2) 

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    See Also:
       Toxicological Abbreviations
       Caffeine (IARC Summary & Evaluation, Volume 51, 1991)