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BIS(2-CHLOROETHYL) ETHER
ICSC: 0417
Peer-Review Status: 10.04.2000 Validated
Dichloroethyl ether
2,2'-Dichloroethyl ether
1,1'-Oxybis(2-chloro)ethane
sym-Dichloroethyl ether
Diethylene glycol dichloride 
CAS #: 111-44-4 RTECS #: KN0875000
UN #: 1916
EC #: 603-029-00-2
EINECS #: 203-870-1
    Formula: C4H8Cl2O / (ClCH2CH2)2O
Molecular mass: 143.02

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Above 55°C explosive vapour/air mixtures may be formed.  Above 55°C use a closed system and ventilation.  In case of fire: keep cylinder cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Cough. Sore throat. Nausea. Vomiting. Burning sensation. Laboured breathing. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Nausea. Vomiting. Burning sensation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T+; R: 10-26/27/28-40; S: (1/2)-7/9-27-28-36/37-45 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTF1-II.
NFPA Code: H3; F2; R1. 
Fireproof. Separated from food and feedstuffs. See Chemical Dangers. Keep in the dark. Well closed. 

IMPORTANT DATA
Physical State; Appearance
CLEAR COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
The substance can form explosive peroxides on exposure to air and light. Decomposes on burning. Decomposes on contact with water. This produces toxic fumes including hydrogen chloride. Reacts with strong oxidants. Reacts violently with chlorosulfonic acid and oleum. 

Occupational exposure limits
TLV: 5 ppm as TWA; 10 ppm as STEL; (skin); A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: 10 ppm, 59 mg/m³; Peak limitation category: I(1); Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Inhalation of of the vapour may cause lung oedema. See Notes. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 178°C
Melting point: -50°C
Relative density (water = 1): 1.22
Vapour pressure, kPa at 25°C: 0.206
Relative vapour density (air = 1): 4.9
Flash point: 55°C c.c.
Auto-ignition temperature: 369°C
Explosive limits, vol% in air: 2.7-?
Octanol/water partition coefficient as log Pow: 1.29  
 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Check for peroxides prior to distillation; eliminate if found.
DCEE, Chlorex are trade names.
Card has been partly updated in October 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations