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DIISOPROPYLAMINE
ICSC: 0449
Peer-Review Status: 04.07.1997 Validated
DIPA
N-(1-Methylethyl)-2-propanamine 
CAS #: 108-18-9 RTECS #: IM4025000
UN #: 1158
EC #: 612-129-00-5
EINECS #: 203-558-5
    Formula: C6H15N / CH3CH(CH3)NHCH(CH3)CH3
Molecular mass: 101.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS! STRICT HYGIENE!   
Inhalation Burning sensation. Cough. Headache. Nausea. Shortness of breath. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Pain. Blisters.  Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision. Severe deep burns.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Burning sensation. Nausea. Shock or collapse. Sore throat.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water. Do NOT wash away into sewer.   
EC Classification
Symbol: F, C; R: 11-20/22-34; S: (1/2)-16-26-36/37/39-45 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GFC-II.
NFPA Code: H3; F3; R0. 
Separated from strong oxidants and strong acids. Cool. Well closed. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on heating. This produces toxic fumes of nitrogen oxides. The substance is a strong base. It reacts with acid and is corrosive. Reacts with oxidants. This generates fire and explosion hazard. Attacks some forms of plastic. 

Occupational exposure limits
TLV: 5ppm as TWA; (skin); (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
Lachrymation. The vapour is corrosive to the eyes and respiratory tract. Inhalation of the vapour may cause lung oedema. See Notes. Contact of the vapour with the eyes may cause visual disturbances. Exposure could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 84°C
Melting point: -61°C
See Notes.
Relative density (water = 1): 0.72
Solubility in water: none
Vapour pressure, kPa at 20°C: 9.3
Relative vapour density (air = 1): 3.5
Flash point: -6°C o.c.
Auto-ignition temperature: 316°C
Explosive limits, vol% in air: 0.8-7.1
Octanol/water partition coefficient as log Pow: 1.64  
The substance is harmful to aquatic organisms. 

NOTES
Other reported melting points: -91°C and -96°C.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations