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3,4-XYLIDINEICSC: 0453
April 2007
CAS #: 95-64-73,4-Dimethylaniline
3,4-Dimethylbenzeneamine
1-Amino-3,4-dimethylbenzene
4-Amino-o-xylene
4-Amino-1,2-xylene
UN #: 3452
EINECS #: 202-437-4

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Above 98°C explosive vapour/air mixtures may be formed.  NO open flames.  Above 98°C use a closed system and ventilation.  Use water spray, carbon dioxide, foam, powder.   

 STRICT HYGIENE!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Dizziness. Drowsiness. Headache. Nausea.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Ingestion.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety spectacles or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion Blue lips, fingernails and skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. 

According to UN GHS Criteria

excl mark;warncancer;health haz
WARNING
Harmful if swallowed
May cause drowsiness and dizziness
May cause damage to blood
May cause damage to blood through prolonged or repeated exposure
Toxic to aquatic life 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 
PACKAGING
Do not transport with food and feedstuffs. 
3,4-XYLIDINE ICSC: 0453
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE SOLID IN VARIOUS FORMS WITH CHARACTERISTIC ODOUR. TURNS REDDISH TO BROWN ON EXPOSURE TO AIR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants. Reacts with hypochlorites. This produces explosive chloroamines. Reacts with acids, acid anhydrides, acid chlorides and halogens. Attacks plastic and rubber. 

Formula: C8H11N / (CH3)2C6H3NH2
Molecular mass: 121.2
Boiling point: 228°C
Melting point: 51°C
Relative density (water = 1): 1.07
Solubility in water, g/100ml at 22°C: 0.38
Vapour pressure, Pa at 25°C: 4
Relative vapour density (air = 1): 4.19
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 98°C
Auto-ignition temperature: 580°C
Octanol/water partition coefficient as log Pow: 1.84  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
Exposure at high levels could cause lowering of consciousness and formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
The substance may have effects on the blood. This may result in anaemia. 


Occupational exposure limits
MAK: skin absorption (H); carcinogen category: 3A 

ENVIRONMENT
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
TLV only established for mixed isomers.
See ICSCs 0451, 0600, 1519, 1686 and 1687. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 23/24/25-33-51/53; S: (1/2)-28-36/37-45-61; Note: C 

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       Toxicological Abbreviations