3,3'-DICHLOROBENZIDINE (ICSC)

3,3'-DICHLOROBENZIDINE	ICSC: 0481

Date of Peer Review: April 1994

3,3'-Dichlorobiphenyl-4,4'-ylenediamine
4,4'-Diamino-3,3'-dichlorobiphenyl

CAS #	91-94-1	C₆H₃ClNH₂C₆H₃ClNH₂/C₁₂H₁₀Cl₂N₂
RTECS #	DD0525000	Molecular mass: 253.1
UN #
EC Annex 1 Index #	612-068-00-4

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, water spray, foam, carbon dioxide.
EXPLOSION

EXPOSURE		PREVENT DISPERSION OF DUST! PREVENT GENERATION OF MISTS! AVOID ALL CONTACT!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Cough. Sore throat.	Avoid inhalation of fine dust and mist. Local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED!	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes		Face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion		Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment (extra personal protection: complete protective clothing including self-contained breathing apparatus).

Do not transport with food and feedstuffs. Note: E
EU Classification
Symbol: T, N
R: 45-21-43-50/53
S: 53-45-60-61

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61G12b

Separated from food and feedstuffs. Well closed.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK

3,3'-DICHLOROBENZIDINE

ICSC: 0481

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
GREY TO PURPLE CRYSTALS.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes including nitrogen oxides and hydrogen chloride.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2006).
MAK: skin absorption (H); Carcinogen category: 2 (DFG 2006).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the respiratory tract.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver. This substance is probably carcinogenic to humans.

PHYSICAL PROPERTIES

Boiling point: 368°C
Melting point: 132-133°C
Solubility in water: none

Auto-ignition temperature: 350°C

ENVIRONMENTAL DATA

The substance is toxic to aquatic organisms.

NOTES

The substance is combustible but no flash point is available in literature. Curithane C126 is a trade name. Card has been partially updated in July 2007: see Occupational Exposure Limits, EU Classification .

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations
       Dichlorobenzidine, 3,3'-  (IARC Summary & Evaluation, Supplement7, 1987)
       Dichlorobenzidine, 3,3'- (IARC Summary & Evaluation, Volume 4, 1974)