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2-HEXANONEICSC: 0489
Methyl n-butyl ketone
n-Butyl methyl ketone
MBK
November 1998
CAS #: 591-78-6
UN #: 1224
EC Number: 209-731-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Flammable.  Above 23°C explosive vapour/air mixtures may be formed.  NO open flames, NO sparks and NO smoking.  Above 23°C use a closed system, ventilation and explosion-proof electrical equipment.  Use alcohol-resistant foam, powder, carbon dioxide.  In case of fire: keep cylinder cool by spraying with water. 

   
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Drowsiness. Headache. Nausea. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Sore throat. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: III 

STORAGE
Fireproof. Separated from strong oxidants. 
PACKAGING
Note: 6 
2-HEXANONE ICSC: 0489
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Reacts violently with oxidants. This generates fire and explosion hazard. Attacks plastics. 

Formula: C6H12O / C4H9COCH3
Molecular mass: 100.2
Boiling point: 126-128°C
Melting point: -57°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 20°C: 1.4
Vapour pressure, kPa at 20°C: 0.36
Relative vapour density (air = 1): 3.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 23°C c.c.
Auto-ignition temperature: 423°C
Explosive limits, vol% in air: 1.2-8.0
Octanol/water partition coefficient as log Pow: 1.38  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and through the skin. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the nervous system. Exposure far above the OEL could cause unconsciousness. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C , on spraying or dispersing much faster. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the nervous system. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 5 ppm as TWA; 10 ppm as STEL; (skin); BEI issued.
MAK: 21 mg/m3, 5 ppm; peak limitation category: II(8); skin absorption (H) 

ENVIRONMENT
 

NOTES
Use of alcoholic beverages enhances the harmful effect.
MBK potentiates the toxicity of some other chemical substances like chloroform, carbon tetrachloride, ethanol.
Depending on the degree of exposure, periodic medical examination is suggested. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T; R: 10-48/23-62-67; S: (1/2)-36/37-45 

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    See Also:
       Toxicological Abbreviations