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METHYL ACETATEICSC: 0507
April 2014
CAS #: 79-20-9Ethyl ester of monoacetic acid
Acetic acid methyl ester
UN #: 1231
EINECS #: 201-185-2

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting.  NO open flames, NO sparks and NO smoking.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Do NOT use compressed air for filling, discharging, or handling.  Use alcohol-resistant foam, foam, powder, carbon dioxide, fine water spray.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Sore throat. Cough. Headache. Drowsiness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Dry skin.  Protective gloves.  Rinse contaminated clothes (fire hazard) with plenty of water. Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Nausea. Vomiting. Weakness. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Collect leaking liquid in sealable containers. Absorb liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

flam;flameexcl mark;warn
DANGER
Highly flammable liquid and vapour
Causes eye irritation
May cause drowsiness or dizziness 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from strong oxidants, strong acids and strong bases. 
PACKAGING
 
METHYL ACETATE ICSC: 0507
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
It reacts with strong oxidants. This generates fire or explosion hazard. It reacts violently with strong acids and strong bases. Attacks rubber and some forms of plastic. 

Formula: C3H6O2 / CH3COOCH3
Molecular mass: 74.1
Boiling point: 57°C
Melting point: -98°C
Relative density (water = 1): 0.93
Solubility in water, g/100ml at 20°C: 24.4 (poor)
Vapour pressure, kPa at 20°C: 23.1
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.3
Flash point: -13°C c.c.
Auto-ignition temperature: 505°C
Explosive limits, vol% in air: 3.1-16
Octanol/water partition coefficient as log Pow: 0.18  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. The substance may cause effects on nervous system. Exposure far above the OEL could cause lowering of consciousness. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
The substance defats the skin, which may cause dryness or cracking. The substance may have effects on the optic nerve. This may result in impaired vision. 


Occupational exposure limits
TLV: 200 ppm as TWA; 250 ppm as STEL.
MAK: 310 mg/m3, 100 ppm; peak limitation category: I(4); pregnancy risk group: C 

ENVIRONMENT
 

NOTES
Do NOT take working clothes home.
The odour warning when the exposure limit value is exceeded is insufficient. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xi; R: 11-36-66-67; S: (2)-16-26-29-33 

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    See Also:
       Toxicological Abbreviations
       METHYL ACETATE (JECFA Evaluation)