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METHYL ISOBUTYL KETONEICSC: 0511
July 1997
CAS #: 108-10-14-Methyl-2-pentanone
Isopropylacetone
Hexone
UN #: 1245
EINECS #: 203-550-1

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Highly flammable.  Vapour/air mixtures are explosive.  NO open flames, NO sparks and NO smoking.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  Use powder, AFFF, foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Cough. Diarrhoea. Dizziness. Headache. Nausea. Sore throat. Unconsciousness. Vomiting. Weakness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin. Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 3; UN Pack Group: II 

STORAGE
Fireproof. Separated from strong oxidants. Well closed. 
PACKAGING
Airtight. 
METHYL ISOBUTYL KETONE ICSC: 0511
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
The substance can form explosive peroxides on exposure to air. Reacts violently with strong oxidants and strong reducing agents. 

Formula: C6H12O / CH3COCH2CH(CH3)2
Molecular mass: 100.2
Boiling point: 117-118°C
Melting point: -84.7°C
Relative density (water = 1): 0.80
Solubility in water, g/100ml at 20°C: 1.91
Vapour pressure, kPa at 20°C: 2.1
Relative vapour density (air = 1): 3.45
Flash point: 14°C c.c.
Auto-ignition temperature: 460°C
Explosive limits, vol% in air: 1.4-7.5
Octanol/water partition coefficient as log Pow: 1.38  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Effects of short-term exposure
The substance and the vapour are irritating to the eyes, skin and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. The substance may cause effects on the central nervous system at high concentrations. This may result in narcosis. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


Occupational exposure limits
TLV: 20 ppm as TWA; 75 ppm as STEL; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued.
MAK: 83 mg/m3, 20 ppm; peak limitation category: I(2); skin absorption (H); pregnancy risk group: C.
EU-OEL: 83 mg/m3, 20 ppm as TWA; 208 mg/m3, 50 ppm as STEL 

ENVIRONMENT
 

NOTES
MIBK is commonly used name.
Check for peroxides prior to distillation; eliminate if found. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xn; R: 11-20-36/37-66; S: (2)-9-16-29; Note: 6 

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    See Also:
       Toxicological Abbreviations
       Methyl isobutyl ketone (EHC 117, 1990)
       Methyl isobutyl ketone (HSG 58, 1991)