IPCS INCHEM Home
PROPYLENE GLYCOL MONOMETHYL ETHER
ICSC: 0551
Peer-Review Status: 10.08.1997 Validated
1-Methoxy-2-propanol
1-Methoxy-propane-2-ol
1-Methoxy-2-hydroxypropane
Propylene glycol methyl ether 
CAS #: 107-98-2 RTECS #: UB7700000
UN #: 3092
EC #: 603-064-00-3
EINECS #: 203-539-1
    Formula: C4H10O2 / H3CCHOHCH2OCH3
Molecular mass: 90.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 38°C explosive vapour/air mixtures may be formed.  Above 38°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Drowsiness. Headache. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Watering of the eyes. Redness. Pain.  Wear safety spectacles or face shield.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Drowsiness. Headache. Nausea.    Rinse mouth. Do NOT induce vomiting. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.   
EC Classification
R: 10; S: (2)-24 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H0; F3; R0.  Fireproof. Cool. Keep in the dark. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
The substance can presumably form explosive peroxides. Reacts with strong oxidants, acid chlorides, acid anhydrides, aluminium and copper. 

Occupational exposure limits
TLV: 100 ppm, 369 mg/m³ as TWA; 150 ppm, 553 mg/m³ as STEL; (ACGIH 1997). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance and the vapour in high concentrations are irritating to the eyes, skin and respiratory tract. Exposure to very high concentrations could cause depression of the central nervous system. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 120°C
Melting point: -96°C
Relative density (water = 1): 0.92
Solubility in water: very good
Vapour pressure, kPa at 20°C: 1.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point: 38°C
Auto-ignition temperature: 270°C
Explosive limits, vol% in air: 1.9-13.1 
 

NOTES
Commercial product may contain impurities which may alter toxic properties.
Check for peroxides prior to distillation; eliminate if found.
Dowanol 33 B, Dowanol PM, Dowtherm 209, Poly-Solv MPM Solvent, PolySolvent M, Propasol Solvent M, UCAR PM Solvent, Ucar Triol HG-170 are trade names.
Card has been partially updated in January 2008: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations