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PROPANIL
ICSC: 0552
Peer-Review Status: 11.04.2014 Validated
3',4'-Dichloropropionanilide
Propanamide, N-(3,4-dichlorophenyl)-
CAS #: 709-98-8 RTECS #: UE4900000
UN #: 3077
EC #: 616-009-00-3
EINECS #: 211-914-6
    Formula: C9H9Cl2NO / C6H3Cl2NHCOCH2CH3
Molecular mass: 218.1

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use dry powder, dry sand, foam, carbon dioxide, water spray. 
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.     
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Blue lips, fingernails and skin. Headache. Dizziness.  Avoid inhalation of dust and mist. Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. See Notes. 
Skin   Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness.  Wear safety spectacles or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion Burning sensation. Confusion. Drowsiness. Nausea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: Xn, N; R: 22-50; S: (2)-22-61 
UN Classification
UN Hazard Class: 9; UN Pack Group: III 
GHS Classification
Signal: Warning
Harmful if swallowed
Very toxic to aquatic life with long lasting effects 
excl mark;warnenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Keep in a well-ventilated room. Store only in original container. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK (not established):. 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of short-term exposure
The substance may cause effects on the central nervous system and blood. See Notes. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Tumours have been detected in experimental animals but may not be relevant to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 351°C
Melting point: 92-93°C
Density (at 25°C): 1.4 g/cm³
Solubility in water, g/l at 20°C: 0.13 (very poor)
Vapour pressure, Pa at 60°C: 0.012
Flash point: >100°C
Octanol/water partition coefficient as log Pow: 3.12  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain. Avoid release to the environment in circumstances different to normal use. 

NOTES
Technical grade propanil is a brown crystalline solid.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Isolate contaminated clothing by sealing in a bag or other container. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Propanil (PIM 440)