IPCS INCHEM Home
beta-PROPIOLACTONE
ICSC: 0555
Peer-Review Status: 10.07.1997 Validated
1,3-Propiolactone
2-Oxetanone
Propanolide 
CAS #: 57-57-8 RTECS #: RQ7350000
UN #: 2810
EC #: 606-031-00-1
EINECS #: 200-340-1
    Formula: C3H4O2
Molecular mass: 72.06

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 74°C explosive vapour/air mixtures may be formed.  Above 74°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Burning sensation. Cough. Headache. Nausea. Shortness of breath. Vomiting.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Skin burns. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation. Sore throat. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+; R: 45-26-36/38; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H0; F2; R0.  Separated from food and feedstuffs. Cooled. Well closed. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
The substance may polymerize due to warming. This generates fire or explosion hazard. 

Occupational exposure limits
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
 

Effects of short-term exposure
The substance is corrosive to the eyes. The substance is irritating to the skin and respiratory tract. 

Effects of long-term or repeated exposure
This substance is probably carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 155°C
Melting point: -33.4°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml: 37
Vapour pressure, kPa at 25°C: 0.3
Flash point: 74°C
Explosive limits, vol% in air: 2.9-? 
 

NOTES
Card has been partially updated in August 2007: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations