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2,4-TOLUENEDIAMINE
ICSC: 0582
Peer-Review Status: 11.04.2014 Validated
2,4-Toluylenediamine
4-Methyl-m-phenylenediamine
2,4-Diaminotoluene
2,4-TDA
CAS #: 95-80-7 RTECS #: XS9625000
UN #: 1709
EC #: 612-099-00-3
EINECS #: 202-453-1
    Formula: C7H10N2 / CH3C6H3(NH2)2
Molecular mass: 122.2

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, dust explosion-proof electrical equipment and lighting.   
 
EXPOSURE   PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!   
Inhalation Cough. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. 
Skin MAY BE ABSORBED! Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles (if molten) or face shield.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-21-25-43-48/22-62-68-51/53; S: 53-45-61; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
Toxic if swallowed
Harmful in contact with skin
May cause an allergic skin reaction
Suspected of causing genetic defects
May cause cancer
Suspected of damaging fertility or the unborn child
May cause damage to liver and kidneys through prolonged or repeated exposure
Toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Well closed. Separated from oxidants and acids. Separated from food and feedstuffs. Store in an area without drain or sewer access. Do NOT store or transport in containers made from aluminium or copper and its alloys. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. TURNS DARK ON EXPOSURE TO AIR. 

Physical dangers
If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc. Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including nitrogen oxides. Reacts with oxidants and acids. This generates fire and explosion hazard. Attacks copper and its alloys and aluminium. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 2; Skin absorption (H); Sensitization of skin (SH); (DFG 2013). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
The substance is mildly irritating to the eyes. The hot liquid may cause severe skin burns. The substance may cause effects on the liver and blood. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the liver and kidneys. This may result in liver function impairment and kidney impairment. This substance is possibly carcinogenic to humans. May cause genetic damage in humans. May cause reproductive toxicity in humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 292°C
Melting point: 99°C
Density: 1.26 kg/l
Solubility in water, g/100ml at 20°C: 3.5
Vapour pressure, kPa at 106.5°C: 0.13
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 149°C
Auto-ignition temperature: 475°C
Octanol/water partition coefficient as log Pow: 0.35  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Do NOT take working clothes home.
Often transported in the molten state. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
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       Toxicological Abbreviations