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ETHYL FORMATE
ICSC: 0623
Peer-Review Status: 05.05.2010 Validated
Formic acid, ethyl ester
Formic ether 
CAS #: 109-94-4 RTECS #: LQ8400000
UN #: 1190
EC #: 607-015-00-7
EINECS #: 203-721-0
    Formula: C3H6O2 / HCOOC2H5
Molecular mass: 74.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use powder, alcohol-resistant foam, water spray, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Heating will cause rise in pressure with risk of bursting. Risk of fire and explosion on contact with strong oxidants.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Shortness of breath. Headache. Drowsiness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Sore throat. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: F, Xn; R: 11-20/22-36/37; S: (2)-9-16-24-26-33 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
Signal: Danger
Highly flammable liquid and vapour
May be harmful if swallowed
Causes serious eye irritation
May cause respiratory irritation 
flam;flameexcl mark;warn

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F3; R0.  Fireproof. Separated from strong oxidants. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Reacts with strong oxidants. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 100ppm as TWA; (ACGIH 2010).
MAK: 100 ppm, 310 mg/m³; Peak limitation category: I(1); Pregnancy risk group: C; Skin absorption (H); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 52-54°C
Melting point: -80°C
Relative density (water = 1): 0.92
Solubility in water, g/100ml at 20°C: 10.5
Vapour pressure, kPa at 20°C: 25.6
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.4
Flash point: -20°C c.c.
Auto-ignition temperature: 440°C
Explosive limits, vol% in air: 2.7-16.5
Octanol/water partition coefficient as log Pow: 0.23  
 

NOTES
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Ethyl formate (FAO Nutrition Meetings Report Series 44a)
       Ethyl formate (WHO Food Additives Series 14)
       ETHYL FORMATE (JECFA Evaluation)