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BUTYLENE OXIDE (STABILIZED)
ICSC: 0636
Peer-Review Status: 04.11.1997 Validated
1,2-Butene oxide
1,2-Epoxybutane
Ethyloxirane 
CAS #: 106-88-7 RTECS #: EK3675000
UN #: 3022
EC #: 603-102-00-9
EINECS #: 203-438-2
    Formula: C4H8O
Molecular mass: 72.12

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use foam, alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with oxidizing agents, acids or metal chlorides.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Confusion. Cough. Dizziness. Headache. Laboured breathing. Nausea. Sore throat. Unconciousness.  Use closed system or ventilation.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Personal protection: filter respirator for organic vapours of low boiling point adapted to the airborne concentration of the substance.  Airtight. 
EC Classification
Symbol: F, Xn; R: 11-20/21/22-36/37/38-40-52/53; S: (2)-9-16-29-36/37-61 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-I+II-9.
NFPA Code: H2; F3; R2. 
Fireproof. Separated from incompatible materials. See Chemical Dangers. Cool. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. The vapour mixes well with air, explosive mixtures are easily formed. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
The substance may polymerize on contact with acids, bases, tin, aluminium and iron chlorides. This generates fire or explosion hazard. Reacts with strong oxidants. This generates fire hazard. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. Exposure at high levels could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the nervous system. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 63.3°C
Melting point: -130°C
Relative density (water = 1): 0.83
Solubility in water, g/100ml at 25°C: 9.5
Vapour pressure, kPa at 20°C: 18.8
Relative vapour density (air = 1): 2.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.3
Flash point: -22°C
Auto-ignition temperature: 439°C
Explosive limits, vol% in air: 3.9-20.6
Octanol/water partition coefficient as log Pow: 0.416  
 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Vapours are uninhibited and may polymerize, blocking valves and vents.
Card has been partly updated in October 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations