IPCS INCHEM Home
DIACETONE ALCOHOL
ICSC: 0647
Peer-Review Status: 19.04.2005 Validated
4-Hydroxy-4-methylpentan-2-one
2-Pentanone, 4-hydroxy-4-methyl-
4-Hydroxy-2-keto-4-methylpentane
4-Hydroxy-4-methyl-2-pentanone 
CAS #: 123-42-2 RTECS #: SA9100000
UN #: 1148
EC #: 603-016-00-1
EINECS #: 204-626-7
    Formula: C6H12O2 / (CH3)2C(OH)CH2COCH3
Molecular mass: 116.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. See Notes.  NO open flames, NO sparks and NO smoking.  Use water spray, alcohol-resistant foam, dry powder, carbon dioxide. 
EXPLOSION Above 58°C explosive vapour/air mixtures may be formed. See Notes.  Above °C use a closed system, ventilation and explosion-proof electrical equipment. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE      
Inhalation Cough. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. 
Skin Redness. Dry skin. MAY BE ABSORBED!  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Cover the spilled material with inert absorbent. Carefully collect remainder.   
EC Classification
Symbol: Xi; R: 36; S: (2)-24/25 
UN Classification
UN Hazard Class: 3; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III.
NFPA Code: H1; F2; R0. 
Fireproof. Separated from acids, bases, amines and oxidants. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating or on burning or on contact with acids, bases and amines. This produces acetone and mesityl alcohol. Reacts violently with oxidants. This produces flammable/explosive gas (hydrogen - see ICSC 0001). 

Occupational exposure limits
TLV: 50ppm as TWA; (ACGIH 2005).
MAK: 20 ppm, 96 mg/m³; Peak limitation category: I(2); Pregnancy risk group: D; Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Exposure far above the OEL could cause lowering of consciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 169-171°C
Melting point: -47°C
Relative density (water = 1): 0.93
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 0.108
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0048
Flash point: 58°C c.c.
Auto-ignition temperature: 640°C
Explosive limits, vol% in air: 1.8-6.9
Octanol/water partition coefficient as log Pow: -0.14 to 1.03 (calculated) 
 

NOTES
This card is only valid for the pure substance.
The technical product may contain up to 5% acetone (see ICSC 0087), resulting in high flammability.
Other UN Classification for technical product: UN hazard class 3, UN pack group II.
Card has been partially updated in August 2007: see Ingestion First Aid, Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Diacetone alcohol (SIDS)