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HEXAMETHYLENEDIAMINE
ICSC: 0659
Peer-Review Status: 26.11.1998 Validated
1,6-Diaminohexane
1,6-Hexanediamine
HMD(A) 
CAS #: 124-09-4 RTECS #: MO1180000
UN #: 2280
EC #: 612-104-00-9
EINECS #: 204-679-6
    Formula: C6H16N2
Molecular mass: 116.24

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames. NO contact with hot surfaces.  Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION     In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Skin burns. Pain. Blisters.  Protective gloves. Protective clothing.  Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Abdominal pain. Burning sensation. Shock or collapse.  Do not eat, drink, or smoke during work.  Rest. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container. 
EC Classification
Symbol: C; R: 21/22-34-37; S: (1/2)-22-26-36/37/39-45 
UN Classification
UN Hazard Class: 8; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-80GC8-II+III.
NFPA Code: H2; F1; R1. 
Separated from strong oxidants and strong acids. Well closed. 

IMPORTANT DATA
Physical State; Appearance
HYGROSCOPIC PELLETS OR FLAKES WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
On combustion, forms toxic and corrosive gases. Upon heating, toxic fumes are formed. This produces toxic fumes. The solution in water is a strong base. It reacts violently with acid and is corrosive. Reacts with oxidants. Attacks many metals in the presence of water. 

Occupational exposure limits
TLV: 0.5ppm as TWA; (ACGIH 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 199-205°C
Melting point: 23-41°C
Relative density (water = 1): 0.93
Solubility in water: soluble
Vapour pressure, Pa at 50°C: 200
Relative vapour density (air = 1): 3.8
Flash point: 85°C c.c.
Auto-ignition temperature: 305°C
Explosive limits, vol% in air: 0.9-7.6 
The substance is toxic to aquatic organisms. 

NOTES
The substance may exist as solid or liquid depending on ambient temperature.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
The recommendations on this Card also apply to Hexamethylenediamine solution, 70-80 %, UN No. 1783.
Card has been partly updated in October 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Hexamethylenediamine  (SIDS)