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p-PHENYLENEDIAMINEICSC: 0805
1,4-Diaminobenzene
1,4-Benzenediamine
p-Aminoaniline
September 1997
CAS #: 106-50-3
UN #: 1673
EC Number: 203-404-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Finely dispersed particles form explosive mixtures in air. Risk of fire and explosion on contact with strong oxidizing agents.  NO open flames.  Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.  Use water spray, powder.   

 STRICT HYGIENE!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Dizziness. Headache. Laboured breathing. See Ingestion.  Use local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Redness. Pain. Swelling of the eyelids. Blurred vision. Loss of vision.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Blue lips, fingernails and skin. Convulsions. Drowsiness. Laboured breathing. Shortness of breath. Vomiting. Weakness.  Do not eat, drink, or smoke during work.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 

STORAGE
Separated from strong oxidants, strong acids, acid anhydrides and food and feedstuffs. Keep in the dark. Well closed. 
PACKAGING
Airtight.
Do not transport with food and feedstuffs. 
p-PHENYLENEDIAMINE ICSC: 0805
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE-TO-SLIGHTLY-RED CRYSTALS. TURNS DARK ON EXPOSURE TO AIR. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on burning. This produces toxic fumes of nitrogen oxides. The substance is a strong reducing agent. It reacts violently with oxidants and strong bases. 

Formula: C6H8N2 / C6H4(NH2)2
Molecular mass: 108.2
Boiling point: 267°C
Melting point: 139-147°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml at 25°C: 4
Vapour pressure, Pa at 100°C: 144
Relative vapour density (air = 1): 3.7
Flash point: 156°C c.c.
Auto-ignition temperature: 400°C
Explosive limits, vol% in air: 1.5-? 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes. Inhalation of dust may cause asthmatic reactions. See Notes. Ingestion could cause swelling of mouth and throat. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Exposure could cause death. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. The substance may have effects on the kidneys. This may result in kidney impairment. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 mg/m3, as TWA; A4 (not classifiable as a human carcinogen).
MAK: (inhalable fraction): 0.1 mg/m3; carcinogen category: 3B; peak limitation category: II(2); pregnancy risk group: C; skin absorption (H); sensitization of skin (SH) 

ENVIRONMENT
The substance is very toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The relation between odour and the occupational exposure limit cannot be indicated.
Rinse contaminated clothes (fire hazard) with plenty of water. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+, N; R: 23/24/25-36-43-50/53; S: (1/2)-28-36/37-45-60-61 

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    See Also:
       Toxicological Abbreviations