2-(ACETYLOXY)BENZOIC ACID (ICSC)

2-(ACETYLOXY)BENZOIC ACID	ICSC: 0822

Date of peer-review: March 1998

Acetylsalicylic acid
2-Acetoxybenzoic acid
Aspirin

CAS #	50-78-2	C₉H₈O₄ / CH₃COOC₆H₄COOH
RTECS #	VO0700000	Molecular mass: 180.2
UN #
EC #

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Powder, water spray, foam, carbon dioxide.
EXPLOSION	Finely dispersed particles form explosive mixtures in air.	Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE		PREVENT DISPERSION OF DUST!
Inhalation	Cough. Sore throat.	Ventilation (not if powder).	Fresh air, rest. Refer for medical attention.
Skin	Redness.	Protective gloves.	Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes	Redness. Pain.	Safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Nausea. Vomiting.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (extra personal protection: P2 filter respirator for harmful particles).

EU Classification
UN Classification

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61G12c

Well closed.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 2001

SEE IMPORTANT INFORMATION ON BACK

2-(ACETYLOXY)BENZOIC ACID

ICSC: 0822

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS TO WHITE CRYSTALS OR WHITE CRYSTALLINE POWDER, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The solution in water is a weak acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 5 mg/m^3 (ACGIH 1997). MAK not established.

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes, the skin, and the respiratory tract. The substance may cause effects on the blood and central nervous system, if ingested in large amounts.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Animal tests show that this substance possibly causes toxic effects upon human reproduction.

PHYSICAL PROPERTIES

Decomposes below boiling point at 140°C
Melting point: 135°C
Density: 1.4 g/cm^3
Solubility in water: poor (0.25 g/100 ml at 15°C)
Vapour pressure, Pa at 25°C: about 0.004

Octanol/water partition coefficient as log Pow: 1.19

ENVIRONMENTAL DATA

NOTES

Acenterine, Acesal, Acetol, Acetophen, Acetosal, Acetosalin, Acetylin, Acetylsal, Acisal, Acylpyrin, Asagran, Aspro, Asteric, Caprin, Duramax, Ecotrin, Empirin, Neuronika, Polopiryna, Rhodine, Salacetin, Xaxa are trade names.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations