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CHLOROACETYL CHLORIDE
ICSC: 0845
Peer-Review Status: 26.03.1998 Validated
Chloroacetic acid chloride
Monochloroacetyl chloride 
CAS #: 79-04-9 RTECS #: AO6475000
UN #: 1752
EC #: 607-080-00-1
EINECS #: 201-171-6
    Formula: C2H2Cl2O / ClCH2COCl
Molecular mass: 112.9

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION     In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Laboured breathing. Burning sensation. Blue lips, fingernails and skin. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Serious skin burns. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Pain. Redness. Blurred vision. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation. Abdominal pain. Diarrhoea. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Cover the spilled material with dry sand. Collect leaking and spilled liquid in sealable containers as far as possible. Then store and dispose of according to local regulations. NEVER direct water jet on liquid. Personal protection: complete protective clothing including self-contained breathing apparatus.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, C, N; R: 14-23/24/25-35-48/23-50; S: (1/2)-7/8-9-26-36/37/39-45-61 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61G61A.
NFPA Code: H3; F0; R1. 
Separated from food and feedstuffs. See Chemical Dangers. Dry. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including phosgene and hydrogen chloride. Reacts violently with water, alcohols, powdered metals and many organics. This generates toxic, fire and explosion hazard. Contact with air generates corrosive gas. 

Occupational exposure limits
TLV: 0.05ppm, 0.23mg/m³ as TWA; (skin); (ACGIH 1997).
TLV: 0.15ppm, 0.69mg/m³ as STEL; (ACGIH 1997).
MAK: Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
Lachrymation. The substance is corrosive to the skin and respiratory tract. The substance is irritating to the eyes. Corrosive on ingestion. Inhalation of of the vapour or aerosol may cause lung oedema. See Notes. The substance may cause effects on the cardiovascular system. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation may cause effects on the lungs. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 106°C
Melting point: -21.8°C
Relative density (water = 1): 1.4
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 2.5
Relative vapour density (air = 1): 3.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.07 
 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Do NOT take working clothes home.
Card has been partially updated in November 2008: see Occupational Exposure Limits, EU Classification, Packaging & labelling. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations