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p-NITROCHLOROBENZENE
ICSC: 0846
Peer-Review Status: 10.08.1997 Validated
1-Chloro-4-nitrobenzene
PCNB
PNCB 
CAS #: 100-00-5 RTECS #: CZ1050000
UN #: 1578
EC #: 610-005-00-5
EINECS #: 202-809-6
    Formula: NO2C6H4Cl
Molecular mass: 157.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Many reactions may cause fire or explosion.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION     Combat fire from a sheltered position. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Blue lips, fingernails and skin. Dizziness. Headache. Nausea. Vomiting. Weakness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes   Wear safety goggles, face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.    Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 23/24/25-40-48/20/21/22-68-51/53; S: (1/2)-28-36/37-45-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-877.
NFPA Code: H3; F1; R2. 
Separated from combustible substances, reducing agents and food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
YELLOWISH CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic gases of nitrogen oxides, hydrogen chloride, phosgene and chlorine. The substance is a strong oxidant. It reacts violently with combustible and reducing materials. 

Occupational exposure limits
TLV: 0.1ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2008).
MAK: Carcinogen category: 3B; Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. 

Effects of short-term exposure
The substance may cause effects on the blood. This may result in formation of methaemoglobin. See Notes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 242°C
Melting point: 82-84°C
Relative density (water = 1): 1.3
Solubility in water: none
Vapour pressure, Pa at 30°C: 20
Relative vapour density (air = 1): 5.44
Flash point: 127°C c.c.
Octanol/water partition coefficient as log Pow: 2.39  
The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated.
Card has been partially updated in November 2008: see Occupational Exposure Limits, EU Classification, Packaging & labelling. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations