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p-NITROCHLOROBENZENEICSC: 0846
1-Chloro-4-nitrobenzene
PCNB
PNCB
August 1997
CAS #: 100-00-5
UN #: 1578
EC Number: 202-809-6

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Many reactions may cause fire or explosion.    NO open flames.    Use water spray, powder, foam, carbon dioxide.  Combat fire from a sheltered position. 

 STRICT HYGIENE!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Blue lips, fingernails and skin. Dizziness. Headache. Nausea. Vomiting. Weakness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes   Wear safety goggles, face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.    Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from combustible substances, reducing agents and food and feedstuffs. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs. 
p-NITROCHLOROBENZENE ICSC: 0846
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
YELLOWISH CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic gases of nitrogen oxides, hydrogen chloride, phosgene and chlorine. The substance is a strong oxidant. It reacts violently with combustible and reducing materials. 

Formula: NO2C6H4Cl
Molecular mass: 157.6
Boiling point: 242°C
Melting point: 82-84°C
Relative density (water = 1): 1.3
Solubility in water: none
Vapour pressure, Pa at 30°C: 20
Relative vapour density (air = 1): 5.44
Flash point: 127°C c.c.
Octanol/water partition coefficient as log Pow: 2.39  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the blood. This may result in the formation of methaemoglobin. See Notes. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued.
MAK: skin absorption (H); carcinogen category: 3B 

ENVIRONMENT
The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is indicated. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 23/24/25-40-48/20/21/22-68-51/53; S: (1/2)-28-36/37-45-61 

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    See Also:
       Toxicological Abbreviations