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DEMETON (MIXED ISOMERS)
ICSC: 0861
Peer-Review Status: 10.09.2002 Validated
 
CAS #: 8065-48-3 RTECS #: TF3150000
UN #: 3018
EC #: 015-118-00-8
    Formula: (C2H5O)2PS.OCH2CH2SC2H5 and (C2H5O)2PO.SCH2CH2SC2H5
Molecular mass: 258.34

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Liquid formulations containing organic solvents may be flammable.  NO open flames.  Use water spray, foam, carbon dioxide, alcohol-resistant foam, dry powder. 
EXPLOSION      
 
EXPOSURE   PREVENT GENERATION OF MISTS! AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Convulsions. Dizziness. Laboured breathing. Nausea. Vomiting. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective clothing. Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes MAY BE ABSORBED! Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Vomiting. See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. See Notes. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+, N; R: 27/28-50; S: (1/2)-28-36/37-45-61 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT6-I.  Separated from strong oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including phosphorus oxides and sulfur oxides. Reacts violently with strong oxidants. Attacks plastics. 

Occupational exposure limits
TLV: 0.05mg/m³ as TWA; (skin); BEI issued; (ACGIH 2002). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in cardiac disorders, convulsions, cyanosis and respiratory failure. Cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 0.27kPa: 134°C
Relative density (water = 1): 1.1
Solubility in water: poor
Vapour pressure, Pa at 20°C: <10
Auto-ignition temperature: 464°C  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds, bees and mammals. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
This substance is a mixture of two isomers: Demeton-O and Demeton-S (see ICSC 0864).
Do NOT take working clothes home.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Depending on the degree of exposure, periodic medical examination is suggested.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Card has been partially updated in November 2008: see 24901000\Occupational Exposure Limits, 24909500\Storage. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
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    See Also:
       Toxicological Abbreviations