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2,4,5-TRICHLOROPHENOL
ICSC: 0879
Peer-Review Status: 11.04.2014 Validated
2,4,5-TCP
1-Hydroxy-2,4,5-trichlorobenzene
CAS #: 95-95-4 RTECS #: SN1400000
UN #: 2020
EC #: 604-017-00-X
EINECS #: 202-467-8
    Formula: C6H3Cl3O / C6H2Cl3(OH)
Molecular mass: 197.5

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames. NO contact with strong oxidizing agents.  Use foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. To remove substance use polyethylene glycol 300 or vegetable oil. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles, face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Dizziness. Headache. Vomiting. Fatigue. Sweating.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn, N; R: 22-36/38-50/53; S: (2)-26-28-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Warning
Harmful if swallowed
Causes skin irritation
Causes serious eye irritation
May cause respiratory irritation
Very toxic to aquatic life 
excl mark;warnenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Separated from strong oxidants and food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
May explode on heating to decomposition. Decomposes on heating and on contact with strong oxidants. This produces toxic and irritating fumes (chlorine, hydrochloric acid). The substance is a weak acid. Reacts in an alkaline medium at high temperatures producing highly toxic chlorinated dioxins. 

Occupational exposure limits
TLV not established.
MAK (2b (not established but data is available)): (DFG 2013). 

Routes of exposure
The substance can be absorbed into the body by ingestion. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached when dispersed. 

Effects of short-term exposure
The substance is severely irritating to the eyes, skin and respiratory tract. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and kidneys. See Notes. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 253°C
Melting point: 67°C
Density: 1.68 g/cm³
Relative vapour density (air = 1): 6.8
Solubility in water, g/l at 20°C: 1.2 (poor)
Flash point: 133°C c.c.
Vapour pressure, Pa at 25°C: 2.9
Octanol/water partition coefficient as log Pow: 3.7  
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and furans.
Depending on the degree of exposure, periodic medical examination is suggested.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Also consult ICSC 0588 2,3,4-trichlorophenol, ICSC 0589 2,3,5-trichlorophenol, ICSC 0590 2,3,6-trichlorophenol and ICSC 1122 2,4,6-trichlorophenol. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
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       Toxicological Abbreviations