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DIOXATHION (ISOMER MIXTURE)ICSC: 0883
March 1998
CAS #: 78-34-2S,S'-(1,4-Dioxane-2,3-diyl) O,O,O',O'-tetraethyl-bis-(phosphorodithioate)
UN #: 3018
EINECS #: 201-107-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  Risk of fire and explosion if formulations contain flammable/explosive solvents.  NO open flames.    In case of fire in the surroundings, use appropriate extinguishing media.   

 PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Laboured breathing. Convulsions. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from food and feedstuffs. Dry. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 
PACKAGING
Do not transport with food and feedstuffs.
Marine pollutant. 
DIOXATHION (ISOMER MIXTURE) ICSC: 0883
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
VISCOUS BROWN LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes above 135°C . This produces toxic fumes including phosphorus oxides and sulfur oxides. Attacks iron and tin surfaces. Hydrolyzed by alkalis. 

Formula: C12H26O6P2S4
Molecular mass: 456.5
Melting point: -20°C
Relative density (water = 1): 1.26 (26°C)
Solubility in water: none
Octanol/water partition coefficient as log Pow: 3.0  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure at high levels could cause death. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 0.1 mg/m3, ppm, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued 

ENVIRONMENT
The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of acute intoxication do not become manifest until 30 minutes to 2 hours.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+, N; R: 24-26/28-50/53; S: (1/2)-28-36/37-45-60-61 

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       Toxicological Abbreviations