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NALED
ICSC: 0925
Peer-Review Status: 21.04.2005 Validated
1,2-Dibromo-2,2-dichloroethyl dimethyl phosphate 
CAS #: 300-76-5 RTECS #: TB9450000
UN #: 3018
EC #: 015-055-00-6
EINECS #: 206-098-3
    Formula: C4H7Br2Cl2O4P
Molecular mass: 380.8

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Vomiting. Dizziness. Convulsions. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Vomiting. Diarrhoea. See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. If liquid: collect leaking liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: Xn, N; R: 21/22-36/38-50; S: (2)-36/37-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT6-III.  Separated from strong oxidants, strong acids and food and feedstuffs. Dry. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID OR WHITE CRYSTALS WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on contact with acids and oxidants. This produces toxic and corrosive fumes including hydrogen bromide, hydrogen chloride and phosphorus oxides. Decomposes on contact with water. This produces dichlorvos and dichloroacetaldehyde. Attacks metals, plastics, rubber and coatings. 

Occupational exposure limits
TLV (inhalable fraction): 0.1mg/m³ as TWA; (skin); (SEN); A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2005).
MAK (inhalable fraction): 1 mg/m³; Peak limitation category: II(2); Pregnancy risk group: C; Skin absorption (H); Sensitization of skin (SH); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Cholinesterase inhibition. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 0.066kPa: 110°C
Melting point: 26.5-27.5°C
Relative density (water = 1): 1.96 (25°C)
Solubility in water: none
Vapour pressure, Pa at 20°C: 0.26
Relative vapour density (air = 1): 13.2
Octanol/water partition coefficient as log Pow: 1.38  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
See ICSC 0690 Dichlorvos (decomposition product of Naled).
Card has been partially updated in November 2008: see Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations