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PHENYLHYDRAZINE
ICSC: 0938
Peer-Review Status: 21.04.2005 Validated
Hydrazinobenzene
Monophenylhydrazine 
CAS #: 100-63-0 RTECS #: MV8925000
UN #: 2572
EC #: 612-023-00-9
EINECS #: 202-873-5
    Formula: C6H8N2 / C6H5NHNH2
Molecular mass: 108.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Above 88°C explosive vapour/air mixtures may be formed.  Above 88°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Cough. Sore throat. Weakness. Dizziness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Dry skin. Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Dizziness. Nausea. Vomiting. Weakness.  Do not eat, drink, or smoke during work.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. If liquid: collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. If solid: sweep spilled substance into containers. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 45-23/24/25-36/38-43-48/23/24/25-68-50; S: 53-45-61; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT1-II.
NFPA Code: H3; F2; R0. 
Separated from strong oxidants and food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW OILY LIQUID OR CRYSTALS. TURNS RED-BROWN ON EXPOSURE TO AIR AND LIGHT. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. Reacts with strong oxidants. Reacts violently with lead dioxide. 

Occupational exposure limits
TLV: 0.1ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: Carcinogen category: 3B; Skin absorption (H); Sensitization of skin (SH); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in haemolysis. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 243.5°C
Melting point: 19.5°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml at 25°C: 14.5
Vapour pressure, Pa at 20°C: 10
Relative vapour density (air = 1): 3.7
Flash point: 88°C c.c.
Auto-ignition temperature: 174°C
Explosive limits, vol% in air: 1.1-?
Octanol/water partition coefficient as log Pow: 1.25  
The substance is toxic to aquatic organisms. 

NOTES
The symptoms of hemolysis do not become manifest until hours have passed.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Phenylhydrazine (CICADS 19, 2000)