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PROPYLENEDIAMINE
ICSC: 0942
Peer-Review Status: 12.10.2006 Validated
1,2-Propanediamine
1,2-Diaminopropane 
CAS #: 78-90-0 RTECS #: TX6650000
UN #: 2258
EC #: 612-100-00-7
EINECS #: 201-155-9
    Formula: C3H10N2 / CH3CH(NH2)CH2NH2
Molecular mass: 74.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents.  Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 33°C explosive vapour/air mixtures may be formed.  Above 33°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Pain. Redness. Skin burns.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention. 
Eyes Pain. Redness. Burns. Loss of vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation. Sore throat. Abdominal pain. Nausea. Vomiting. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: C; R: 10-21/22-35; S: (1/2)-26-37/39-45 
UN Classification
UN Hazard Class: 8; UN Subsidiary Risks: 3; UN Pack Group: II 
GHS Classification
Signal: Danger
Flammable liquid and vapour
Causes severe skin burns and eye damage
May be harmful if swallowed and enters airways
Harmful to aquatic life 
corrflam;flamecancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-80S2258 or 80GCF1-II.
NFPA Code: H3; F3; R0. 
Fireproof. Separated from food and feedstuffs, strong oxidants, acids, acid anhydrides and acid chlorides. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
HYGROSCOPIC COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
No data. 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. The substance is a strong base. It reacts violently with acid and is corrosive. Reacts with acid anhydrides, acid chlorides and strong oxidants. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
Serious by all routes of exposure. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. See Notes. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 119°C
Melting point: -12°C
Relative density (water = 1): 0.9
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 1.0
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Flash point: 33 °C c.c.
Auto-ignition temperature: 416°C
Explosive limits, vol% in air: 2.2-11.1
Octanol/water partition coefficient as log Pow: -1.8  
The substance is harmful to aquatic organisms. 

NOTES
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Other melting points: -37 °C (technical product). 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations