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ISOAMYL NITRITE
ICSC: 1012
Peer-Review Status: 26.11.1998 Validated
Amyl nitrite
Nitrous acid, 3-methyl butyl ester
3-Methylbutanol nitrite
Isopentyl alcohol nitrite 
CAS #: 110-46-3 RTECS #: NT0187500
UN #: 1113
EC #: 007-020-00-9
EINECS #: 203-770-8
    Formula: C5H11N02
Molecular mass: 117.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Many reactions may cause fire or explosion. Heating will cause rise in pressure with risk of bursting.  NO open flames, NO sparks and NO smoking.  Use water spray, alcohol-resistant foam. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE   PREVENT GENERATION OF MISTS! STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Blue lips, fingernails and skin. Confusion. Convulsions. Dizziness. Headache. Sweating. Nausea. Unconciousness. Vomiting. Flushing of the face. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.  Airtight.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: F, Xn; R: 11-20/22; S: (2)-16-24-46 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30G30.
NFPA Code: H1; F; R2. 
Fireproof. Separated from strong oxidants. Cool. Well closed. 

IMPORTANT DATA
Physical State; Appearance
YELLOW LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
May explode on heating. Decomposes on burning. This produces toxic gases including nitrogen oxides. Reacts with oxidants. This generates fire and explosion hazard. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation and through the skin. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance may cause effects on the blood and cardiovascular system. This may result in cardiac disorders and formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 97-99°C
Relative density (water = 1): 0.875
Solubility in water: none
Vapour pressure, kPa at 20°C: 3.5
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: 3°C
Auto-ignition temperature: 209°C  
 

NOTES
Combustion in a confined space may turn into detonation.
Depending on the degree of exposure, periodic medical examination is indicated.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partially updated in November 2008: see EU Classification, Packaging & labelling. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations