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ENDRIN
ICSC: 1023
Peer-Review Status: 10.03.2000 Validated
 
CAS #: 72-20-8 RTECS #: IO1575000
UN #: 2761
EC #: 602-051-00-X
EINECS #: 200-775-7
    Formula: C12H8Cl6O
Molecular mass: 380.9

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation See Ingestion.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Ingestion.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Dizziness. Weakness. Headache. Nausea. Vomiting. Convulsions.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus.  Do not transport with food and feedstuffs.
Severe marine pollutant. 
EC Classification
Symbol: T+, N; R: 24-28-50/53; S: (1/2)-22-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61G41A.
NFPA Code: H3; F0; R; 0. 
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes above 245°C . This produces hydrogen chloride and phosgene. 

Occupational exposure limits
TLV: 0.1mg/m³ as TWA; (skin); A4 (not classifiable as a human carcinogen); (ACGIH 2008).
MAK (inhalable fraction): 0.1 mg/m³; Peak limitation category: II(8); Pregnancy risk group: C; Skin absorption (H); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in convulsions and death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 245°C
Melting point: 200°C
Density: 1.7 g/cm³
Solubility in water at 25°C: none
Vapour pressure at 25°C: negligible
Octanol/water partition coefficient as log Pow: 5.34  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees, birds and mammals. It is strongly advised not to let the chemical enter into the environment because it is persistent. Bioaccumulation of this chemical may occur in fish and seafood. Avoid release to the environment in circumstances different to normal use. 

NOTES
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Card has been partially updated in November 2008: see Occupational Exposure Limits, Storage. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Endrin (EHC 130, 1992)
       Endrin (HSG 60, 1991)
       Endrin (FAO Meeting Report PL/1965/10/1)
       Endrin (AGP:1970/M/12/1)
       Endrin (WHO Pesticide Residues Series 4)
       Endrin (WHO Pesticide Residues Series 5)
       Endrin (IARC Summary & Evaluation, Volume 5, 1974)