IPCS INCHEM Home
HEXAFLUOROACETONEICSC: 1057
1,1,1,3,3,3-Hexafluoro-2-propanone
Perfluoroacetone
April 2000
CAS #: 684-16-2
UN #: 2420
EC Number: 211-676-3

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.        In case of fire in the surroundings, use appropriate extinguishing media.  In case of fire: keep cylinder cool by spraying with water. 

 STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Burning sensation. Laboured breathing. Shortness of breath. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. 
Eyes Redness. Pain.  Wear safety spectacles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion      

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Remove gas with fine water spray. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 2.3; UN Subsidiary Risks: 8 

STORAGE
Fireproof if in building. Cool. 
PACKAGING
 
HEXAFLUOROACETONE ICSC: 1057
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS GAS WITH CHARACTERISTIC ODOUR. 

Physical dangers
The gas is heavier than air. 

Chemical dangers
Decomposes at 550°C. This produces toxic and corrosive fumes. Reacts vigorously with water and moisture. This produces a highly acidic hydrate. Attacks glass and most metals. 

Formula: C3F6O / CF3COCF3
Molecular mass: 166.0
Boiling point: -28°C
Melting point: -129°C
Solubility in water: reaction, releasing heat
Relative vapour density (air = 1): 5.7
Octanol/water partition coefficient as log Pow: 1.46  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and through the skin. 

Effects of short-term exposure
The substance is severely irritating to the eyes, skin and respiratory tract. Inhalation of this gas may cause lung oedema. See Notes. Rapid evaporation of the liquid may cause frostbite. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful concentration of this gas in the air will be reached very quickly on loss of containment. 

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes malformations in human babies. Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 ppm as TWA; (skin) 

ENVIRONMENT
 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
  EC Classification
 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.
    See Also:
       Toxicological Abbreviations