IPCS INCHEM Home
PHORATEICSC: 1060
March 2000
CAS #: 298-02-2O,O-Diethyl-S-(ethylthio)methyl phosphorodithioate
UN #: 3018
EINECS #: 206-052-2

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible.    NO open flames.    Use water spray, foam, powder, carbon dioxide.   

 STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Convulsions. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes See Inhalation.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation. Abdominal cramps. Diarrhoea. Vomiting.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. 

According to UN GHS Criteria

skull;toxiccancer;health hazenviro;aqua
DANGER
Fatal if swallowed, in contact with skin or if inhaled
Causes damage to nervous system
Causes damage to the nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 
PACKAGING
 
PHORATE ICSC: 1060
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes under the influence of heat. This produces fumes of phosphorus oxides and sulfur oxides. 

Formula: C7H17O2PS3
Molecular mass: 260.4
Melting point: -42.9°C
Relative density (water = 1): 1.2
Solubility in water: none
Vapour pressure, Pa at 20°C: 0.1
Flash point: 160°C o.c.
Octanol/water partition coefficient as log Pow: 3.9  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin, through the eyes and by ingestion. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 0.05 mg/m3, ppm, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds and bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Do NOT take working clothes home.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+, N; R: 27/28-50/53; S: (1/2)-28-36/37-45-60-61 

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    See Also:
       Toxicological Abbreviations
       Phorate (Pesticide residues in food: 1977 evaluations)
       Phorate (Pesticide residues in food: 1982 evaluations)
       Phorate (Pesticide residues in food: 1984 evaluations)
       Phorate (Pesticide residues in food: 1985 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1994 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1996 evaluations Part II Toxicological)