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METHYLACETOACETATEICSC: 1086
November 2003
CAS #: 105-45-3Acetoacetic acid methyl ester
Butanoic acid, 3-oxo-, methyl ester
1-Methoxybutane-1,3-dione
EINECS #: 203-299-8

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible.  Above 77°C explosive vapour/air mixtures may be formed.  NO open flames.  Above 77°C use a closed system and ventilation.  Use alcohol-resistant foam, powder, carbon dioxide.   

   
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Cough. Dizziness. Drowsiness. Headache. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water. 

According to UN GHS Criteria

 

Transportation
UN Classification
 

STORAGE
Separated from oxidants. 
PACKAGING
 
METHYLACETOACETATE ICSC: 1086
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces irritating fumes. Reacts with oxidants. 

Formula: C5H8O3
Molecular mass: 116.1
Boiling point: 171.7°C
Melting point: -27°C
Relative density (water = 1): 1.08
Solubility in water, g/100ml: 50
Vapour pressure, kPa at 20°C: 0.17
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 77°C c.c.
Auto-ignition temperature: 280°C
Explosive limits, vol% in air: 1.4-14.5
Octanol/water partition coefficient as log Pow: -0.26  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Exposure could cause lowering of consciousness. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of long-term or repeated exposure
 


Occupational exposure limits
 

ENVIRONMENT
 

NOTES
 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xi; R: 36; S: (2)-26 

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       Toxicological Abbreviations