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ACETOPHENONE
ICSC: 1156
Peer-Review Status: 24.10.1994 Validated
1-Phenylethanone
Phenyl methyl ketone
Acetylbenzene 
CAS #: 98-86-2 RTECS #: AM5250000
EC #: 606-042-00-1
EINECS #: 202-708-7
    Formula: C8H8O / C6H5COCH3
Molecular mass: 120.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use alcohol-resistant foam, powder, carbon dioxide. 
EXPLOSION Above 82°C explosive vapour/air mixtures may be formed.  Above 82°C use a closed system and ventilation.   
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Headache. Dizziness. Drowsiness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety spectacles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
Symbol: Xn; R: 22-36; S: (2)-26 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F2; R0.  Separated from strong oxidants. Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID OR WHITE CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
 

Occupational exposure limits
 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes. The substance may cause effects on the central nervous system. Exposure at high levels could cause unconsciousness. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 202°C
Melting point: 20°C
Relative density (water = 1): 1.03
Solubility in water: poor
Vapour pressure, kPa at 15°C: 0.133
Relative vapour density (air = 1): 4.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1
Flash point: 82°C o.c.
Auto-ignition temperature: 571°C
Octanol/water partition coefficient as log Pow: 1.58  
 

NOTES
Use of alcoholic beverages enhances the harmful effect.
Hypnone is a trade name. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       ACETOPHENONE (JECFA Evaluation)