ACETOPHENONE (ICSC)

ACETOPHENONE	ICSC: 1156

Date of peer-review: October 1994

1-Phenylethanone
Phenyl methyl ketone
Acetylbenzene

CAS #	98-86-2	C₈H₈O / C₆H₅COCH₃
RTECS #	AM5250000	Molecular mass: 120.1
UN #
EC #	606-042-00-1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Alcohol-resistant foam, powder, carbon dioxide.
EXPLOSION	Above 82°C explosive vapour/air mixtures may be formed.	Above 82°C use a closed system, ventilation.

EXPOSURE		PREVENT GENERATION OF MISTS!
Inhalation	Headache. Dizziness. Drowsiness.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	Dry skin.	Protective gloves.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes	Redness. Pain.	Safety spectacles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Nausea. (Further see Inhalation).	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: A/P2 filter respirator for organic vapour and harmful dust).

EU Classification
Symbol: Xn
R: 22-36
S: (2-)26
UN Classification

EMERGENCY RESPONSE

STORAGE

NFPA Code: H1; F2; R0

Separated from strong oxidants. Ventilation along the floor.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 2001

SEE IMPORTANT INFORMATION ON BACK

ACETOPHENONE

ICSC: 1156

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID OR WHITE CRYSTALS, WITH CHARACTERISTIC ODOUR.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 ppm; 49 mg/m^3 (ACGIH 1993-1994).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes. The substance may cause effects on the central nervous system. Exposure at high level may result in unconsciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin.

PHYSICAL PROPERTIES

Boiling point: 202°C
Melting point: 20°C
Relative density (water = 1): 1.03
Solubility in water: poor
Vapour pressure, kPa at 15°C: 0.133
Relative vapour density (air = 1): 4.1

Relative density of the vapour/air-mixture at 20°C (air = 1): 1
Flash point: 82°C o.c.
Auto-ignition temperature: 571°C
Octanol/water partition coefficient as log Pow: 1.58

ENVIRONMENTAL DATA

NOTES

Use of alcoholic beverages enhances the harmful effect. Hypnone is a trade name.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations
       ACETOPHENONE (JECFA Evaluation)