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ISOBUTYLAMINE
ICSC: 1253
Peer-Review Status: 20.04.2005 Validated
2-Methylpropylamine
2-Methyl-1-propanamine
1-Amino-2-methylpropane 
CAS #: 78-81-9 RTECS #: NP9900000
UN #: 1214
EINECS #: 201-145-4
    Formula: C4H11N / (CH3)2CHCH2NH2
Molecular mass: 73.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Burning sensation. Cough. Shortness of breath. Laboured breathing. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Pain. Redness. Skin burns.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Cautiously neutralize spilled liquid. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container. 
EC Classification
 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GFC-II.
NFPA Code: H3; F3; R0. 
Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on burning. This produces toxic gases including nitrogen oxides. The solution in water is a medium strong base. Reacts violently with acids and oxidants. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: 5 ppm, 15 mg/m³; Peak limitation category: I(2); Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 68-69°C
Melting point: -85°C
Relative density (water = 1): 0.72
Solubility in water: miscible
Vapour pressure, kPa at 18.8°C: 13.3
Relative vapour density (air = 1): 2.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -9.0°C c.c.
Auto-ignition temperature: 378°C
Explosive limits, vol% in air: 3.4-9
Octanol/water partition coefficient as log Pow: 0.73  
 

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       ISOBUTYLAMINE (JECFA Evaluation)