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FLOCOUMAFEN
ICSC: 1267
Peer-Review Status: 26.10.1995 Validated
4-Hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin
4-Hydroxy-3-(1,2,3,4-tetrahydro-3-(4-((4-(trifluoromethyl)phenyl)methoxy)phenyl)- 1-naphthalenyl)-2H-1-benzopyran-2-one 
CAS #: 90035-08-8 RTECS #: DJ3100300
UN #: 3027
EC #: 607-375-00-5
EINECS #: 421-960-0
    Formula: C33H25F3O4
Molecular mass: 542.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! See Notes. 
Inhalation See Ingestion.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Ingestion.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes   Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Dizziness. Drowsiness. Nausea. Shock or collapse. Spontaneous bleeding from various sites. See Notes.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment.  Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+, N; R: 26/27/28-48/23/24/25-50/53; S: (1/2)-28-36/37/39-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-I.  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
ODOURLESS COLOURLESS-TO-CREAM-COLOURED CRYSTALLINE SOLID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen fluoride (see ICSC 0283) and carbon monoxide (see ICSC 0023). 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance may cause effects on the blood. This may result in impairment of blood clotting. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: 181-191°C (cis-isomer)
Melting point: 163-166°C (trans-isomer)
Relative density (water = 1): 1.2
Solubility in water, g/100ml: 0.0001 (none)
Vapour pressure at 25°C: negligible
Octanol/water partition coefficient as log Pow: 4.7 (estimated) 
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to terrestrial organisms. Bioaccumulation of this chemical may occur in aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
The symptoms of bleeding do not become manifest until days later.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Do NOT take working clothes home.
Storm and Stratagem are trade names.
Card has been partly updated in April 2005.
See sections EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations