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m-PHENYLENEDIAMINE
ICSC: 1302
Peer-Review Status: 23.03.1999 Validated
m-Diaminobenzene
1,3-Benzenediamine
3-Aminoaniline
1,3-Phenylenediamine 
CAS #: 108-45-2 RTECS #: SS7700000
UN #: 1673
EC #: 612-147-00-3
EINECS #: 203-584-7
    Formula: C6H8N2 / C6H4(NH2)2
Molecular mass: 108.14

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Blue lips, fingernails and skin. Confusion. Convulsions. Dizziness. Headache. Nausea. Unconciousness.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 23/24/25-36-43-50/53-68; S: (1/2)-28-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1673-S.  Separated from strong oxidants and food and feedstuffs. Keep in the dark. Well closed. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALS. TURNS RED ON EXPOSURE TO AIR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. Reacts with strong oxidants. 

Occupational exposure limits
TLV: 0.1mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: Carcinogen category: 3B; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the kidneys and blood. This may result in renal failure and formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the kidneys. This may result in renal failure. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 284-287°C
Melting point: 62-63°C
Density: 1.14 g/cm³
Solubility in water: soluble
Vapour pressure, Pa at 99.8°C: 133
Relative vapour density (air = 1): 3.7
Flash point: 187°C c.c.
Auto-ignition temperature: 560°C
Octanol/water partition coefficient as log Pow: -0.33  
The substance is toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Direct Brown BR, Direct Brown GG, Developer C, Developer H, Developer M, Developer 11 are trade names.
See also ICSC0805 p-Phenylenediamine.
Card has been partly updated in October 2004 and April 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations