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METHOXYCHLORICSC: 1306
1,1-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene)
1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane
Dimethoxy-DDT
March 1999
CAS #: 72-43-5
EC Number: 200-779-9

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, powder, alcohol-resistant foam, carbon dioxide.   

 PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation See Ingestion.  Use local exhaust or breathing protection.  Fresh air, rest. 
Skin   Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes   Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Convulsions. Diarrhoea. Nausea. Vomiting.  Do not eat, drink, or smoke during work. Wash hands before eating.  Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. 

According to UN GHS Criteria

 

Transportation
UN Classification
 

STORAGE
Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs. 
METHOXYCHLOR ICSC: 1306
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-LIGHT-YELLOW CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive gases including hydrogen chloride (see ICSC 0163). Reacts with oxidants. Attacks some plastics and rubber. 

Formula: C16H15Cl3O2
Molecular mass: 345.7
Melting point: 89°C
Density: 1.4 g/cm³
Solubility in water: none
Vapour pressure: negligible
Octanol/water partition coefficient as log Pow: 4.68/5.08  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Effects of short-term exposure
 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 10 mg/m3, as TWA; A4 (not classifiable as a human carcinogen).
MAK: (inhalable fraction): 1 mg/m3; peak limitation category: II(8); skin absorption (H); pregnancy risk group: B 

ENVIRONMENT
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Ingestion in large amounts may cause effects on the liver, kidneys and central nervous system.
Temperature of decomposition unknown in literature.
Depending on the degree of exposure, periodic medical examination is suggested.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
See ICSC 0034. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations
       Methoxychlor (FAO Meeting Report PL/1965/10/1)
       Methoxychlor (Pesticide residues in food: 1977 evaluations)
       Methoxychlor (IARC Summary & Evaluation, Volume 5, 1974)
       Methoxychlor (IARC Summary & Evaluation, Volume 20, 1979)