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TETRAHYDROPHTHALIC ANHYDRIDEICSC: 1372
March 2001
CAS #: 85-43-84-Cyclohexene-1,2-dicarboxylic anhydride
3a,4,7,7a-Tetrahydro-1,3-isobenzofurandione
THPA
1,2,3,6-Tetrahydrophthalic anhydride
UN #: 2698
EINECS #: 201-605-4

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible.    NO open flames.    Use water spray, powder, foam, carbon dioxide.   

 PREVENT DISPERSION OF DUST!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Cough. Sore throat. Wheezing. Shortness of breath.  Use local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin Redness. Burning sensation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain. Blurred vision. Severe deep burns.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: P2 filter respirator for harmful particles. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 8; UN Pack Group: III 

STORAGE
Separated from food and feedstuffs. Dry. Well closed. 
PACKAGING
Do not transport with food and feedstuffs. 
TETRAHYDROPHTHALIC ANHYDRIDE ICSC: 1372
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALLINE POWDER. 

Physical dangers
 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces corrosive fumes. Reacts with oxidants. Reacts with water. This produces heat and tetrahydrophthalic acid. 

Formula: C8H8O3 / C6H8(CO)2O
Molecular mass: 152.2
Boiling point at 6.7kPa: 195°C
Melting point: 102°C
Density: 1.4 g/cm³
Solubility in water: reaction
Vapour pressure, Pa at 20°C: 1
Relative vapour density (air = 1): 5.3
Flash point: 157°C o.c.
Auto-ignition temperature: 450°C  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. 


Occupational exposure limits
 

ENVIRONMENT
The substance is harmful to aquatic organisms. 

NOTES
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance.
For cis-isomer the CAS number is 935-79-5. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xn; R: 41-42/43-52/53; S: (2)-22-24-26-37/39-61; Note: C 

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       Toxicological Abbreviations