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o-PHENYLENEDIAMINE
ICSC: 1441
Peer-Review Status: 10.09.2002 Validated
o-Diaminobenzene
1,2-Benzenediamine
2-Aminoaniline
1,2-Phenylenediamine 
CAS #: 95-54-5 RTECS #: SS7875000
UN #: 1673
EC #: 612-145-00-2
EINECS #: 202-430-6
    Formula: C6H8N2 / C6H4 (NH2)2
Molecular mass: 108.16

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent deposition of dust.   
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Blue lips, fingernails and skin. Confusion. Convulsions. Dizziness. Headache. Nausea. Unconciousness.  Use local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 20/21-25-36-40-43-50/53-68; S: (1/2)-28-36/37-45-60-61; Note: C 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H; F1; R0.
Transport Emergency Card: TEC (R)-61S1673-S. 
Separated from food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
BROWN-TO-YELLOW CRYSTALS. TURNS DARK ON EXPOSURE TO LIGHT. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. 

Occupational exposure limits
MAK: Carcinogen category: 3B; Sensitization of skin (SH); (DFG 2002). 

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes. The substance is mildly irritating to the skin and respiratory tract. The substance may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 256-258°C
Melting point: 103-104°C
Solubility in water, g/100ml at 35°C: 0.4
Vapour pressure, kPa at 20°C: 0.0013
Relative vapour density (air = 1): 3.73
Flash point: 156°C c.c.
Explosive limits, vol% in air: 1.5-?
Octanol/water partition coefficient as log Pow: 0.15 (calculated) 
The substance is very toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Also consult ICSC 0805 p-Phenylenediamine and ICSC 1302 m-Phenylenediamine. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations