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n-BUTYRONITRILE
ICSC: 1465
Peer-Review Status: 05.06.2003 Validated
Butanenitrile
Butyric acid nitrile
1-Cyanopropane
n-Propyl cyanide 
CAS #: 109-74-0 RTECS #: ET8750000
UN #: 2411
EC #: 608-005-00-5
EINECS #: 203-700-6
    Formula: C4H7N / CH3CH2CH2CN
Molecular mass: 69.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents.  Use water spray, foam, alcohol-resistant foam, dry powder, carbon dioxide. 
EXPLOSION Above 17°C explosive vapour/air mixtures may be formed.  Above 17°C use a closed system, ventilation and explosion-proof electrical equipment. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Dizziness. Laboured breathing. Nausea. Vomiting. Weakness. Confusion. Convulsions. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. See Notes. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective clothing. Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: self-contained breathing apparatus.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 10-23/24/25; S: (1/2)-45 
UN Classification
UN Hazard Class: 3; UN Subsidiary Risks: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GFT1-II.
NFPA Code: H3; F3; R; 0. 
Fireproof. Separated from strong oxidants, strong reducing agents, strong bases, strong acids and food and feedstuffs. Keep in a well-ventilated room. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
Decomposes on burning. Decomposes on contact with hot surfaces, flames or acids. This produces toxic and corrosive fumes including hydrogen cyanide and nitrogen oxides. Reacts violently with strong acids, strong bases, strong oxidants and strong reducing agents. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by ingestion, by inhalation and through the skin. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C ; on spraying or dispersing much faster. 

Effects of short-term exposure
The vapour is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cellular respiration (inhibition). This may result in convulsions, cardiac disorders and respiratory failure. Exposure at high levels could cause death. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 116-118°C
Melting point: -112°C
Relative density (water = 1): 0.8
Solubility in water, g/100ml at 25°C: 3
Vapour pressure, kPa at 20°C: 2
Relative vapour density (air = 1): 2.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Flash point: 17°C
Auto-ignition temperature: 501°C
Explosive limits, vol% in air: 1.6-?
Octanol/water partition coefficient as log Pow: 0.5/0.6  
This substance may be hazardous to the environment. Special attention should be given to birds. 

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Depending on the degree of exposure, periodic medical examination is suggested. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations