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PYRETHRUMICSC: 1475
November 2003
CAS #: 8003-34-7Buhach
Pyrethrum extract
Pyrethrum oleoresin
EINECS #: 232-319-8

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible.  Risk of fire and explosion on contact with oxidizing agents.  NO open flames. NO contact with oxidizing agents.    Use water spray, powder, foam, carbon dioxide.   

 PREVENT GENERATION OF MISTS!  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Headache. Nausea. Vomiting.  Use ventilation (not if powder), local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Pain.  Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Numbness of tongue and lips. Convulsions. Muscle paralysis. Muscular fibrillation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
 

STORAGE
Separated from strong oxidants and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. 
PACKAGING
Do not transport with food and feedstuffs. 
PYRETHRUM ICSC: 1475
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
PALE YELLOW MOBILE OIL WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces smoke and irritating fumes. Reacts with strong oxidants. This generates fire and explosion hazard. 


Decomposes at 170°C at 0.01 kPa
Density: 0.84-0.86 g/cm³
Solubility in water: none
Flash point: 76°C c.c.
Octanol/water partition coefficient as log Pow: 5.9 (pyrethrin II)
Octanol/water partition coefficient as log Pow: 4.3 (pyrethrin I) 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. 


Occupational exposure limits
TLV: 5 mg/m3, ppm, as TWA; A4 (not classifiable as a human carcinogen).
MAK: sensitization of skin (SH).
EU-OEL: 1 mg/m3 as TWA 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees. 

NOTES
Pyrethrum is a mixture of pyrethrin I and II, cinerin I and II, and jasmolin I and II.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Do NOT take working clothes home.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: Xn, N; R: 20/21/22-50/53; S: (2)-13-60-61 

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    See Also:
       Toxicological Abbreviations