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n-PROPYL NITRATE
ICSC: 1513
Peer-Review Status: 22.04.2004 Validated
Nitric acid, propyl ester
Monopropyl nitrate 
CAS #: 627-13-4 RTECS #: UK0350000
UN #: 1865
EINECS #: 210-985-0
    Formula: C3H7NO3
Molecular mass: 105.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents, combustible substances or reducing agents.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with combustible substances. Explosive.  Do NOT expose to friction or shock. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.  In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. 
 
EXPOSURE      
Inhalation Blue lips, fingernails and skin. Dizziness. Headache. Nausea. Confusion. Convulsions. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. See Notes. 
Skin Redness.  Protective gloves.  Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Further see Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.   
EC Classification
 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F3; R3; OX.
Transport Emergency Card: TEC (R)-30GF1-I+II. 
Well closed. Cool. Fireproof. Separated from strong oxidants, combustible substances and reducing agents. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Heating may cause violent combustion or explosion. May decompose explosively on shock, friction or concussion. Decomposes on burning. This produces nitrogen oxides. The substance is a strong oxidant. It reacts violently with combustible and reducing materials. Reacts violently with strong oxidants. 

Occupational exposure limits
TLV: 25 ppm as TWA; 40 ppm as STEL; BEI issued; (ACGIH 2004).
MAK: 25 ppm, 110 mg/m³; Peak limitation category: II(2); (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the respiratory tract, eyes and skin. Inhalation of high concentrations may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 110°C
Relative density (water = 1): 1.05
Solubility in water: poor
Vapour pressure, kPa at 20°C: 2.4
Relative vapour density (air = 1): 3.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06
Flash point: 20°C c.c.
Auto-ignition temperature: 175°C
Explosive limits, vol% in air: 2-100 
 

NOTES
Combustion in a confined space may turn into detonation.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations