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2,6-XYLIDINE
ICSC: 1519
Peer-Review Status: 19.04.2007 Validated
2,6-Dimethylaniline
2,6-Dimethylbenzeneamine
1-Amino-2,6-dimethylbenzene
2-Amino-1,3-xylene 
CAS #: 87-62-7 RTECS #: ZE9275000
UN #: 1711
EC #: 612-161-00-X
EINECS #: 201-758-7
    Formula: C8H11N / (CH3)2C6H3NH2
Molecular mass: 121.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, carbon dioxide, foam, powder. 
EXPLOSION Above 96°C explosive vapour/air mixtures may be formed.  Above 96°C use a closed system and ventilation.   
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Dizziness. Drowsiness. Headache. Nausea.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Ingestion.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear safety spectacles or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion Blue lips, fingernails and skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: Xn, N; R: 20/21/22-37/38-40-51/53; S: (2)-23-25-36/37-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Warning
Combustible liquid
Harmful if swallowed
Suspected of causing cancer
May cause drowsiness and dizziness
May cause damage to blood
May cause damage to blood and liver through prolonged or repeated exposure 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1711-L.
NFPA Code: H3; F0; R0. 
Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens and food and feedstuffs. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
YELLOW LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR. 

Physical dangers
The vapour is heavier than air. 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants. Reacts with hypochlorites. This produces explosive chloroamines. Reacts with acids, acid anhydrides, acid chlorides and halogens. Attacks plastic and rubber. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body in hazardous amounts by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
Exposure at high levels could cause lowering of consciousness. Exposure at high levels could cause formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
The substance may have effects on the blood. This may result in anaemia. The substance may have effects on the liver. This substance is possibly carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 215°C
Melting point: 11.2°C
Relative density (water = 1): 0.98
Solubility in water, g/100ml at 20°C: 0.7
Vapour pressure, kPa at 20°C: 0.02
Relative vapour density (air = 1): 4.2
Flash point: 91°C
Auto-ignition temperature: 520°C
Explosive limits, vol% in air: 1.3-6.9
Octanol/water partition coefficient as log Pow: 1.84  
This substance may be hazardous to the environment. Special attention should be given to aquatic organisms. 

NOTES
Do NOT take working clothes home.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
TLV only established for mixed isomers.
See also ICSC 0600 (Xylidine, mixed isomers), 0451 (2,3-Xylidine), 1562 (2,4-Xylidine), 0453 (3,4-Xylidine), 1686 (2,5-Xylidine), 1687 (3,5-Xylidine).
Card has been partially updated in January 2008: see GHS classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations