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ISOBUTYL CHLOROFORMATE
ICSC: 1594
Peer-Review Status: 18.10.2005 Validated
Isobutyl chlorocarbonate
2-Methylpropyl chloroformate
Formic acid, chloro-, isobutyl ester
Carbonochloridic acid, 2-methylpropyl ester 
CAS #: 543-27-1 UN #: 2742
EINECS #: 208-840-1
    Formula: C5H9ClO2 / (CH3)2CHCH2OCOCl
Molecular mass: 136.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking.  NO water. Use dry powder, carbon dioxide, alcohol-resistant foam. 
EXPLOSION Above 27°C explosive vapour/air mixtures may be formed.  Above 27°C use a closed system, ventilation and explosion-proof electrical equipment.  In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. 
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sore throat. Burning sensation. Cough. Laboured breathing. Shortness of breath. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Pain. Skin burns.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Burning sensation. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable dry plastic containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Unbreakable packaging.
Put breakable packaging into closed unbreakable container. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3 and 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTFC-II.  Fireproof. Dry. Well closed. Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes. Reacts with water and moisture. This produces hydrogen chloride. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: 0.2 ppm, 1.1 mg/m³; Peak limitation category: I(2); Pregnancy risk group: C; (DFG 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of of the vapour may cause lung oedema. See Notes. The effects may be delayed. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 129°C
Density: 1.04 g/cm³
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 2.2
Relative vapour density (air = 1): 4.71
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 27°C c.c.
Octanol/water partition coefficient as log Pow: 1.54 (calculated) 
The substance is toxic to aquatic organisms. 

NOTES
Reacts violently with fire extinguishing agents such as water.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations