2-BUTYNE-1,4-DIOL (ICSC)

2-BUTYNE-1,4-DIOL	ICSC: 1733

Date of Peer Review: November 2008

1,4-Butynediol
1,4-Dihydroxy-2-butyne
But-2-yne-1,4-diol
2-Butynediol

CAS #	110-65-6	C₄H₆O₂/OHCH2CCCH2OH
RTECS #	ES0525000	Molecular mass: 86.1
UN #	2716
EC Annex 1 Index #	603-076-00-9
EC/EINECS #	203-788-6

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Water spray, alcohol-resistant foam, dry powder, carbon dioxide.
EXPLOSION	Risk of explosion on contact with base(s), oxidants, halogens.

EXPOSURE		STRICT HYGIENE!
Inhalation	Cough. Sore throat. Burning sensation. Shortness of breath. Laboured breathing.	Ventilation (not if powder).	Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Skin	Redness. Pain. Skin burns.	Protective clothing. Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention.
Eyes	Redness. Pain. Burns.	Face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Burns in mouth and throat. Burning sensation in the throat and chest. Abdominal pain.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Evacuate danger area! Consult an expert! Personal protection: Chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.

Do not transport with food and feedstuffs.
EU Classification
Symbol: C, T
R: 21-23/25-34-43-48/22
S: (1/2-)25-26-36/37/39-45-46
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
GHS Classification
Danger
Toxic if swallowed
Harmful in contact with skin
Toxic if inhaled mist
Causes severe skin burns and eye damage
May cause allergic skin reaction
May cause damage to liver, kidney and blood through prolonged or repeated exposure
Harmful to aquatic life

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61GT2-III

Separated from incompatible materials. See Chemical Dangers. Cool. Store in an area without drain or sewer access.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities Š IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK

2-BUTYNE-1,4-DIOL

ICSC: 1733

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
YELLOW SOLID IN VARIOUS FORMS

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes. Reacts violently with anhydrides, acid chlorides, mercury salts and alkaline hydroxides or chlorides, causing explosion hazard.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: (Inhalable fraction) 0.2 mg/mł Skin absorption (H). Sensitization of skin (Sh). Peak limitation category: I(1). Pregnancy risk group: C. (DFG 2008).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Serious local effects by all routes of exposure.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
Corrosive. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood, resulting in anaemia, and kidneys and liver, resulting in tissue lesions. Repeated or prolonged contact may cause skin sensitization.

PHYSICAL PROPERTIES

Decomposes at >160 °C
Melting point: 58°C
Relative density (water = 1): 1.1
Solubility in water, g/100 ml at 20°C: 75 (good)
Vapour pressure, Pa at 20°C: 0.2
Relative vapour density (air = 1): 3.0

Flash point: 152°C
Auto-ignition temperature: 335°C
Octanol/water partition coefficient as log Pow: -0.73

ENVIRONMENTAL DATA

The substance is harmful to aquatic organisms.

NOTES

There is no odour warning even when toxic concentrations are present. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

Š IPCS, CEC 2005

    See Also:
       Toxicological Abbreviations