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BLASTICIDIN-S
ICSC: 1758
Peer-Review Status: 09.06.2011 Validated
1-(4-amino-1,2-dihydro-2-oxopyrimidin-1-yl)-4-[(S)-3-amino-=5-(1-methylguanidino)valeramido]-1,2,3,4-tetradeoxy-beta-D-erythro-hex-2-enopyranuronic acid
(S)-4-4[[3-amino-5-[(aminoiminomethyl)methylamino]-=1-oxopentyl]amino]-1-[4-amino-2-oxo-1(2H)-pyrimidinyl]-1,2,3,4-tetradeoxy-beta-D-erythro-hex-=2-enopyranuronic acid 
CAS #: 2079-00-7 RTECS #: EC4900000
UN #: 2588
EC #: 607-155-00-9
    Formula: C17H26N8O5
Molecular mass: 422.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use powder, water spray, foam, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Sore throat. Cough. Headache. Laboured breathing. See Ingestion.  Avoid inhalation of dust. Use local exhaust or breathing protection.  Fresh air, rest. Refer immediately for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention if skin irritation occurs. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Abdominal pain. Weakness. Dizziness. Nausea. Vomiting. Diarrhoea. Fever. Shock or collapse.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T+; R: 28; S: (1/2)-24/25-36/37-45 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Fatal if swallowed
May be harmful in contact with skin
Causes mild skin irritation
Causes serious eye irritation
May cause respiratory irritation
Causes damage to the gastrointestinal tract if swallowed 
skull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Separated from food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides. 

Occupational exposure limits
TLV not established.
MAK (not established):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the respiratory tract and skin. Corrosive on ingestion. Exposure at high levels could cause death. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Decomposes at 253-255°C
Solubility in water, g/100ml at 20°C: >3 (moderate)
Vapour pressure, Pa at 25°C: (negligible)
Octanol/water partition coefficient as log Pow: -4.7  
Environmental effects from the substance have not been investigated adequately. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations