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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

FENBENDAZOLE
Chemical names: METHYL 5-(PHENYLTHIO)-2-BENZIMIDAZOLECARBAMATE
Synonyms: PANACUR®, SAFE-GUARD®, HOE 881, AXILUR®
Functional class: VETERINARY DRUG (ANTHELMINTHIC AGENT)
Latest evaluation: 1998
ADI: 0-0.007 mg/kg bw
Comments/MRLs: Group ADI for febantel, fenbendazole and oxfendazole; group MRLs for febantel, fenbendazole and oxfendazole determined as the sum of fenbendazole, oxfendazole and oxfendazole sulfone, expressed as oxfendazole sulfone equivalents, in mg/kg tissue, mg/l milk: Muscle, kidney and fat (cattle, horses, pigs, sheep and goats): 0.1; Liver (cattle, horses, pigs, sheep and goats): 0.5: Milk (cattle and sheep): 0.1
Report: TRS 888-JECFA 50/13
Residues: FNP 41/11-JECFA 50/49
Tox monograph: FAS 41-JECFA 50/23
Previous status: 1995, TRS 864-JECFA 45/21, FNP 41/8-JECFA 45/99, FAS 36-JECFA 45/51. 0-0.004. GROUP TEMPORARY ADI FOR FEBANTEL, FENBENDAZOLE AND OXFENDAZOLE. MRLs (TEMPORARY, GROUP MRL FOR FEBANTEL, FENBENDAZOLE AND OXFENDAZOLE DETERMINED AS THE SUM OF FENBENDAZOLE, OXFENDAZOLE AND OXFENDAZOLE SULFONE, EXPRESSED AS OXFENDAZOLE SULFONE EQUIVALENTS): MUSCLE, KIDNEY AND FAT (CATTLE, PIGS AND SHEEP): 0.1; LIVER (CATTLE, PIGS AND SHEEP): 0.5: MILK (CATTLE AND SHEEP): 0.1. TE. TMRL
1991, TRS 815-JECFA 38/18, FNP 41/4-JECFA 38/57, FAS 29-JECFA 38/45. 0-0.025 (TEMPORARY) (MRLs (TEMPORARY; GROUP MRL FOR FEBANTEL, FENBENDAZOLE AND OXFENDAZOLE, INDIVIDUALLY OR IN COMBINATION): MUSCLE, FAT AND KIDNEY (CATTLE, SHEEP AND PIGS): 0.1; LIVER (CATTLE, SHEEP AND PIGS): 0.5; MILK (CATTLE): 0.1). TE. TMRL
 
12 Nov 01    




    See Also:
       Toxicological Abbreviations
       Fenbendazole (WHO Food Additives Series 29)