FAO Nutrition Meetings Report Series No. 40A,B,C WHO/Food Add./67.29 TOXICOLOGICAL EVALUATION OF SOME ANTIMICROBIALS, ANTIOXIDANTS, EMULSIFIERS, STABILIZERS, FLOUR-TREATMENT AGENTS, ACIDS AND BASES The content of this document is the result of the deliberations of the Joint FAO/WHO Expert Committee on Food Additives which met at Rome, 13-20 December, 19651 Geneva, 11-18 October, 19662 1 Ninth Report of the Joint FAO/WHO Expert Committee on Food Additives, FAO Nutrition Meetings Report Series, 1966 No. 40; Wld Hlth Org. techn. Rep. Ser., 1966, 339 2 Tenth Report of the Joint FAO/WHO Expert Committee on Food Additives, FAO Nutrition Meetings Report Series, 1967, in press; Food and Agriculture Organization of the United Nations World Health Organization 1967 AMMONIUM CARBONATE Definition Ammonium carbonate consists of ammonium hydrogen carbonate (NH4HCO3) and ammonium carbonate (NH2.COONH4) in varying proportions. It yields not less than 30 per cent, and not more than 33 per cent. of NH3. Description Ammonium carbonate occurs as a white powder or hard, white or translucent masses, having a strong odour of ammonia. Uses As a buffer and neutralizing agent. Evaluation See Magnesium Oxide CALCIUM CARBONATE Synonym Chalk Chemical name Calcium carbonate Empirical formula CaCO3 Molecular weight 100.09 Definition Calcium carbonate contains not less than 98.0 per cent. CaCO3, after drying. Description Calcium carbonate occurs as a white micro-crystalline powder. It is odourless and tasteless. Uses As a neutralizing agent, a nutrient supplement, and a firming agent. Evaluation See Magnesium Oxide MAGNESIUM CARBONATE Definition Magnesium carbonate contains the equivalent of not less than 24 per cent. and not more than 26.4 per cent. of Mg. Description Magnesium carbonate is a basic hydrated magnesium carbonate or a normal hydrated magnesium carbonate or a mixture of the two. It occurs as odourless, light, white, friable masses or as a bulky white powder. Uses As a neutralizing or anticaking agent. Evaluation See Magnesium Oxide POTASSIUM CARBONATE Chemical name Potassium carbonate Empirical formula K2CO3 . 1 1/2 H2O Molecular weight 138.21 (anhydrous) Definition Potassium carbonate contains not less than 99.0 per cent. K2CO3, after drying. Description Potassium carbonate occurs as a white crystalline or granular powder. It is odourless, has a strong alkaline taste, and is very deliquescent, It is available commercially as the anhydrous salt and as the crystalline material. Use As a neutralizing agent. Evaluation See Magnesium Oxide SODIUM CARBONATE Chemical name Sodium carbonate Empirical formula Na2CO3. x H2O Molecular weight 105.99 (anhydrous) Definition Sodium carbonate contains not less than 99.0 per cent. of Na2CO3, after drying. Description Sodium carbonate occurs as colourless crystals or as a white, granular or crystalline powder. Use As neutralizing agent. Evaluation See Magnesium Oxide AMMONIUM HYDROGEN CARBONATE Chemical name Ammonium hydrogen carbonate; Ammonium bicarbonate Empirical formula NH4HCO3 Molecular weight 79.06 Definition Ammonium, hydrogen carbonate contains not less than 99 per cent. and not more than the equivalent of 100.5 per cent. NH4 Description Ammonium hydrogen carbonate occurs as white crystals or as crystalline powder having a slight odour of ammonia. Uses As a buffer and neutralizing agent. Evaluation See Magnesium Oxide POTASSIUM HYDROGEN CARBONATE Chemical name Potassium hydrogen carbonate; Potassium bicarbonate Empirical formula KHCO3 Molecular weight 100.12 Definition Potassium bicarbonate contains not less than 99 per cent. and not more than the equivalent of 101 per cent. KHCO3 after drying. Description Potassium hydrogen carbonate occurs as odourless, colourless, crystals or as a white powder or granules. Uses As a neutralizing and leavening agent. Evaluation See Magnesium Oxide SODIUM HYDROGEN CARBONATE Synonym Baking soda Chemical names Sodium hydrogen carbonate; Sodium bicarbonate Empirical formula NaHCO3 Molecular weight 84.01 Definition Sodium hydrogen carbonate contains not less than 99.0 per cent. NaHCO3 after drying. Description Sodium bicarbonate occurs as an odourless white crystalline powder. Uses As neutralizing and leavening agent. Evaluation See Magnesium Oxide AMMONIUM HYDROXIDE Synonyms Strong ammonia solution Chemical name Ammonium hydroxide Empirical formula NH4OH Molecular weight 35.05 Definition Ammonium hydroxide is an aqueous solution containing not less than 27 per cent. and not more than 30 per cent. by weight of NH3. Description Ammonium hydroxide occurs as a clear, colourless solution of NH3 having an exceedingly pungent characteristic odour. Use As a neutralizing agent. Evaluation See Magnesium Oxide CALCIUM HYDROXIDE Chemical name Calcium hydroxide. Empirical formula Ca(OH)2 Molecular weight 74.09 Definition Calcium hydroxide contains not less than 95 per cent. Ca(OH)2. Description Calcium hydroxide occurs as a white powder, possessing a slightly bitter alkaline taste. Use As a neutralizing agent. Evaluation See Magnesium Oxide MAGNESIUM HYDROXIDE Chemical name Magnesium hydroxide Empirical formula Mg(OH)2 Molecular weight 58.34 Definition Magnesium hydroxide contains not less than 95 per cent. Mg(OH)2, after drying. Description Magnesium hydroxide occurs as an odourless, white, bulky powder with a slight alkaline taste. Uses As a neutralizing, drying and colour retention agent. Evaluation See Magnesium Oxide. POTASSIUM HYDROXIDE Chemical name Potassium hydroxide Empirical formula KOH Molecular weight 56.11 Definition Potassium hydroxide contains not less than 85 per cent. of total alkali calculated as KOH. Description Potassium hydroxide occurs as white or nearly white pellets, flakes, sticks, fused masses or other forms. Use As a neutralizing agent. Evaluation See Magnesium Oxide SODIUM HYDROXIDE Chemical name Sodium hydroxide Empirical formula NaOH Molecular weight 40.00 Definition Sodium hydroxide contains not less than 95 per cent. of total alkali calculated as NaOH. Description Sodium hydroxide occurs as white, or nearly white pellets, flakes, sticks, fused masses or other forms. Use As neutralizing agent. Evaluation See Magnesium Oxide CALCIUM OXIDE Chemical name Calcium oxide Empirical formula CaO Molecular weight 56.08 Definition Calcium oxide, after heating at about 800° contains not less than 95 per cent. CaO. Description Calcium oxide occurs as an odourless, hard, white or greyish white mass or granules or a white to greyish white powder. Caution Protect eyes when adding water. Use As a neutralizing agent. Evaluation See Magnesium Oxide MAGNESIUM OXIDE Chemical name Magnesium oxide Empirical formula MgO Molecular weight 40.31 Definition Magnesium oxide contains not less than 96 per cent. of MgO after heating at about 800°. Description Magnesium oxide occurs as a very bulky white powder, known as light magnesium oxide, or as a relatively dense, white powder, known as heavy magnesium, oxide. Five grams of light magnesium oxide occupy a volume of approximately 40 to 50 ml, while 5 g of heavy magnesium oxide occupy a volume of approximately 10 to 20 ml. Use As a neutralizing agent. Evaluation Provided the nutritional implications or the over-all dietary intake of cations derived from these additives are taken into account, there appear to be no toxicological grounds to limit their use in accordance with good manufacturing practice.
See Also: Toxicological Abbreviations