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    ANNEX 4

        RECOMMENDATIONS ON COMPOUNDS ON THE AGENDA
                                                                                               

    Substances                    Acceptable Daily Intake       Recommended Maximum Residue
                                  (ADI) for human beings        Limit (MRL
                                  and other toxicological
                                  recommendations
                                                                                               

    -Adrenoceptor-blocking
    agent

    Carazolol                     0.01 g per kg of body        Muscle and fat (cattle
                                  weight1                       and pigs): 5 g/kg2
                                                                Liver and kidney (cattle
                                                                and pigs): 30 g/kg2

    Anthelmintic agents

    Febantel                      0-10 g per kg of body        Muscle, fat and kidney
                                  weight1                       (cattle, sheep, and pigs):
                                                                100 g/kg2,3

    Fenbendazole                  0-25 g per kg of body        Liver (cattle, sheep,
                                  weight1                       and pigs): 500 g/kg2,3

    Oxfendazole                   0-4 g per kg of body         Milk (cattle):
                                  weight1                       100 g/l2,3

    Antimicrobial agents

    Spiramycin                    0.5 g per kg of body         Muscle (cattle and
                                  weight1                       pigs): 50 g/kg2
                                                                Liver (cattle and
                                                                pigs): 300 g/kg2
                                                                Kidney (cattle and
                                                                pigs): 200 g/kg2
                                                                Milk (cattle):
                                                                150 g/l2

    Sulfadimidine                 0-4 g per kg of body         Allocated in 19894
                                  weight1
    Tylosin                       Not allocated                 No MRLs allocated6
                                                                                               

    RECOMMENDATIONS ON COMPOUNDS ON THE AGENDA cont'd
                                                                                               

    Substances                    Acceptable Daily Intake       Recommended Maximum Residue
                                  (ADI) for human beings        Limit (MRL
                                  and other toxicological
                                  recommendations
                                                                                               

    Tranquillizers

    Azaperone                     Not allocated5                No MRLs allocated6

    Chlorpromazine                Not allocated5                No MRLs allocated6,7

    Propionylpromazine            Not allocated5                No MRLs allocated6.7
                                                                                               

    Notes to Annex 4

    1.   Temporary acceptance 

    2.   Temporary MRL 

    3.   Group MRL for febantel, fenbendazole, and oxfendazole individually or
         in combination. The MRL value is the sum of the concentrations of
         fenbendazole, oxfendazole, and oxfendazole sulfone, calculated as
         oxfendazole sulfone equivalents.

    4.   WHO Technical Report Series, No. 788, 1989.

    5.   Insufficient toxicological information was available to establish
         an ADI.

    6.   MRLs were not established because an ADI was not allocated.

    7.   Insufficient information was available to establish an MRL.
    





















    See Also:
       Toxicological Abbreviations