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WHO FOOD ADDITIVES SERIES: 51

ANNEX 4

Recommendations on compounds on the agenda and further information required

Antimicrobial agents

Neomycin

Acceptable daily intake:

The ADI of 060 g/kg bw (established at the forty-seventh meeting of the Committee (WHO TRS 876, 1998)) was maintained.

Residue definition:

Neomycin

Recommended maximum residue limits (MRLs)a

Species

Liver (g/kg)

Kidney (g/kg)

Milk (g/kg)

Cattle

500

10 000

1500

a The MRLs of 500 g/kg for cattle muscle and fat and all other MRLs recommended at the forty-seventh meeting of the Committee (WHO TRS 876, 1998) were maintained.

Flumequine

Acceptable daily intake:

The ADI established at the forty-eighth meeting of the Committee (WHO TRS 879, 1998) was withdrawn.

Residue definition:

The MRLs for cattle, pigs, sheep, chickens and trout established at previous meetings (WHO TRS 879, 1998; WHO TRS 900, 2001) were withdrawn.

Antiprotozoal agent

Imidocarb

Acceptable daily intake:

010 mg/kg bw (established at the fiftieth meeting of the Committee (WHO TRS 888, 1999))

Residue definition:

Imidocarb free base

Recommended maximum residue limits (MRLs)

Species

Fat (g/kg)

Kidney (g/kg)

Liver (g/kg)

Milk (g/kg)

Muscle (g/kg)

Cattle

50

2000

1500

50

300

Insecticides

Deltamethrin

Intake considerations:

The Joint FAO/WHO Expert Meeting on Pesticide Residues performed a dietary risk assessment and estimated that the theoretical intake of deltamethrin residues from pesticide use would account for 25% of the ADI, equivalent to 150 g (FAO Plant Production and Protection Paper No. 172, 2002). The sum of the theoretical concentrations of deltamethrin residues from use as a veterinary drug and as a pesticide use would be no more than 415 g, equivalent to 68% of the ADI.

Residue definition:

The Committee affirmed that the MRLs recommended at the fifty-second meeting (WHO TRS 893, 2000) were compatible with the ADI.

Dicyclanil

Acceptable daily intake:

00.007 mg/kg bw (established at the fifty-fourth meeting of the Committee (WHO TRS 900, 2001))

Residue definition:

Dicyclanil

Recommended maximum residue limits (MRLs)

Species

Muscle (g/kg)

Liver (g/kg)

Kidney (g/kg)

Fat (g/kg)

Sheep

150

125

125

200

Trichlorfon (metrifonate)

Acceptable daily intake:

The Committee amended the ADI for trichlorfon from
020 g/kg to 02 g/kg bw

Residue definition:

The Committee confirmed the MRL for cows milk and the guidance levels for muscle, liver, kidney and fat of cattle recommended at the fifty-fourth meeting (WHO TRS 900, 2001).

Production aid

Carbadox

Acceptable daily intake:

The Committee confirmed the opinion, expressed at its thirty-sixth meeting (WHO TRS 799 1990), that an ADI could not be established.

Residue definition:

The Committee decided to withdraw the MRLs of carbadox recommended at the thirty-sixth meeting (WHO TRS 799 1990).














    See Also:
       Toxicological Abbreviations